PET and SPECT Imaging of the Brain: History, Technical Considerations, Applications, and Radiotracers

被引:21
作者
Davis, Korbin M. [1 ]
Ryan, Joshua L. [1 ]
Aaron, Vasantha D. [1 ]
Sims, Justin B. [1 ]
机构
[1] Indiana Univ Sch Med, Dept Radiol & Imaging Sci, 550 N Univ Blvd,Room 0663, Indianapolis, IN 46202 USA
关键词
POSITRON-EMISSION-TOMOGRAPHY; ATTENUATION CORRECTION; COMPUTED-TOMOGRAPHY; FDG-PET; GLUCOSE-UTILIZATION; LEWY BODIES; DEMENTIA; DIAGNOSIS; SCANNER; SYSTEM;
D O I
10.1053/j.sult.2020.08.006
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Advances in nuclear medicine have revolutionized our ability to accurately diagnose patients with a wide array of neurologic pathologies and provide appropriate therapy. The development of new radiopharmaceuticals has made possible the identification of regional differences in brain tissue composition and metabolism. In addition, the evolution of 3-dimensional molecular imaging followed by fusion with computed tomography and magnetic resonance imaging have allowed for more precise localization of pathologies. This review will introduce single photon emission computed tomography and positron emission tomographic imaging of the brain, including the history of their development, technical considerations, and a brief overview of pertinent radiopharmaceuticals and their applications. Semin Ultrasound CT MRI 41:521-529 (c) 2020 Elsevier Inc. All rights reserved.
引用
收藏
页码:521 / 529
页数:9
相关论文
共 63 条
[1]  
Abbaspour Samira, 2017, World J Nucl Med, V16, P101, DOI 10.4103/1450-1147.203079
[2]   Response Assessment in Neuro-Oncology working group and European Association for Neuro-Oncology recommendations for the clinical use of PET imaging in gliomas [J].
Albert, Nathalie L. ;
Weller, Michael ;
Suchorska, Bogdana ;
Galldiks, Norbert ;
Soffietti, Riccardo ;
Kim, Michelle M. ;
La Fougere, Christian ;
Pope, Whitney ;
Law, Ian ;
Arbizu, Javier ;
Chamberlain, Marc C. ;
Vogelbaum, Michael ;
Ellingson, Ben M. ;
Tonn, Joerg C. .
NEURO-ONCOLOGY, 2016, 18 (09) :1199-1208
[3]  
AMBROSE J, 1973, BRIT J RADIOL, V46, P148
[4]   Phase 3 Assessment of the Automated Bone Scan Index as a Prognostic Imaging Biomarker of Overall Survival in Men With Metastatic Castration-Resistant Prostate Cancer A Secondary Analysis of a Randomized Clinical Trial [J].
Armstrong, Andrew J. ;
Anand, Aseem ;
Edenbrandt, Lars ;
Bondesson, Eva ;
Bjartell, Anders ;
Widmark, Anders ;
Sternberg, Cora N. ;
Pili, Roberto ;
Tuvesson, Helen ;
Nordle, Orjan ;
Carducci, Michael A. ;
Morris, Michael J. .
JAMA ONCOLOGY, 2018, 4 (07) :944-951
[5]  
Bag AK, 2016, BRAIN TUMOR IMAGING, P156
[6]  
Beyer T, 2000, J NUCL MED, V41, P1369
[7]  
Blankespoor SC, 1994, P 1994 IEEE NUCL SCI
[8]   Gamma camera-mounted anatomical X-ray tomography: technology, system characteristics and first images [J].
Bocher, M ;
Balan, A ;
Krausz, Y ;
Shrem, Y ;
Lonn, A ;
Wilk, M ;
Chisin, R .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE, 2000, 27 (06) :619-627
[9]   18F-Fluciclovine PET/CT in Suspected Residual or Recurrent High-Grade Glioma [J].
Bogsrud, Trond V. ;
Londalen, Ayca ;
Brandal, Petter ;
Leske, Henning ;
Panagopoulos, Ioannis ;
Borghammer, Per ;
Bach-Gansmo, Tore .
CLINICAL NUCLEAR MEDICINE, 2019, 44 (08) :605-611
[10]  
Brownell G., 1999, HIST POSITRON IMAGIN