Trans-arterial chemoembolization (TACE) of liver metastases from colorectal cancer using irinotecan-eluting beads: Preliminary results

被引：0
|
作者：
Aliberti, C.
Tilli, M.
Benea, G.
Fiorentini, G.
机构：
[1] Gen Hosp San Giuseppe, Dept Oncol, Empoli, Italy
[2] Dept Radiol AUSL Ferrara, Ferrara, Italy
来源：
ANTICANCER RESEARCH | 2006年 / 26卷 / 5B期
关键词：
chemoembolization; drug-eluting beads; irinotecan; liver metastases; colorectal cancer;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Purpose: The purpose of the study was to evalutate the feasibility of irinotecan drug-eluting beads (DC Bead (TM)) administered as trans-arterial chemoembolization (TACE) in patients with liver metastases from colorectal cancer (CRC). Patients and Methods: Ten patients with liver metastases from CRC were treated with TACE adopting itinotecan-eluting beads at a dose of 100 mg every 3 weeks. Computed Tomography (CT) was performed 24h before and after TACE. Results: TACE with irinotecan eluting beads was found to be feasible and well-tolerated. Right tipper quadrant pain (RUQP) lasting 4 days (range 2-7) was reported by all the patients. After 30 days, a reduction > 50% of CEA levels and of the lesional contrast enhancement was observed in all the patients. Conclusion: Irinotecan drug-eluting beads administered as TACE were shown to be active and safe in patients with liver metastases from CRC.
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收藏
页码：3793 / 3795
页数：3
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