Azathioprine induced serious portal hypertension : a case series of three IBD patients and review of the literature

被引：1
作者：
Dooremont, D. [1 ,2 ]
Decaestecker, J. [1 ]
De Wulf, D. [1 ]
Ghillebert, G. [1 ]
Van Vlierberghe, H. [2 ]
Van Dorpe, J. [3 ]
Baert, F. [1 ]
机构：
[1] H Hart Ziekenhuis Roeselare Menen VZW, Dept Gastroenterol, Roeselare, Belgium
[2] Ghent Univ Hosp, Dept Gastroenterol & Hepatol, Ghent, Belgium
[3] H Hart Ziekenhuis Roeselare Menen VZW, Dept Anatomopathol, Roeselare, Belgium
来源：
ACTA GASTRO-ENTEROLOGICA BELGICA | 2013年 / 76卷 / 03期
关键词：
case series; IBD; azathioprine; nodular regenerative hyperplasia; portal hypertension; NODULAR REGENERATIVE HYPERPLASIA; BOWEL-DISEASE PATIENTS; LIVER; ALLOPURINOL;
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
We report 3 male IBD patients (2 Crohn's Disease, 1 Ulcerative Colitis) developing thrombocytopenia and splenomegaly on azathioprine treatment. All patients were diagnosed with significant portal hypertension due to histological proven nodular regenerative hyperplasia (NRH) of the liver. In two of three patients, liver function tests remained completely normal. In addition we provide a short literature review of azathioprine induced NRH covering etiology, imaging, pathology, prognosis and treatment.
引用
收藏
页码：342 / 346
页数：5
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