Many BCR-ABL1 compound mutations reported in chronic myeloid leukemia patients may actually be artifacts due to PCR-mediated recombination

被引:25
作者
Parker, Wendy T. [1 ,2 ]
Phillis, Stuart R. [1 ]
Yeung, David T. O. [1 ,3 ,4 ]
Hughes, Timothy P. [3 ,4 ,5 ]
Scott, Hamish S. [1 ,2 ,4 ,6 ]
Branford, Susan [1 ,2 ,4 ,6 ]
机构
[1] SA Pathol, Ctr Canc Biol, Dept Genet & Mol Pathol, Adelaide, SA 5000, Australia
[2] Univ S Australia, Sch Pharm & Med Sci, Adelaide, SA 5001, Australia
[3] SA Pathol, Ctr Canc Biol, Dept Hematol, Adelaide, SA 5000, Australia
[4] Univ Adelaide, Sch Med, Adelaide, SA, Australia
[5] South Australian Hlth & Med Res Inst, Adelaide, SA, Australia
[6] Univ Adelaide, Sch Mol & Biomed Sci, Adelaide, SA, Australia
关键词
BCR-ABL; INHIBITOR; RESISTANCE; THERAPY;
D O I
10.1182/blood-2014-05-573485
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:153 / 155
页数:3
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