A Review of Signal Transduction of Endothelin-1 and Mitogen-activated Protein Kinase-related Pain for Nanophysiotherapy

被引：10

作者：

Lee, Lim-Kyu ^{[1
]}

Kim, Ju-Hyun ^{[1
]}

Kim, Mee-Young ^{[1
]}

Lee, Jeong-Uk ^{[1
]}

Yang, Seung-Min ^{[1
]}

Jeon, Hye-Joo ^{[1
]}

Lee, Won-Deok ^{[1
]}

Noh, Ji-Woong ^{[1
]}

Kwak, Taek-Yong ^{[2
]}

Jang, Sung-Ho ^{[3
]}

Lee, Tae-Hyun ^{[4
]}

Kim, Bokyung ^{[5
]}

Kim, Junghwan ^{[6
]}

机构：

[1] Yongin Univ, Dept Phys Therapy, Grad Sch, Lab Hlth Sci & Nanophysiotherapy, Yongin 449714, South Korea

[2] Yongin Univ, Dept Taekwondo Instructor Educ, Yongin 449714, South Korea

[3] Yongin Univ, Coll Martial Arts, Dept Judo, Yongin 449714, South Korea

[4] Yongin Univ, Coll Martial Arts, Dept Combat Martial Arts Training, Yongin 449714, South Korea

[5] Konkuk Univ, Sch Med, Dept Physiol, Inst Funct Genom, Seoul, South Korea

[6] Yongin Univ, Dept Phys Therapy, Coll Publ Hlth & Welf, Yongin 449714, South Korea

来源：

JOURNAL OF PHYSICAL THERAPY SCIENCE | 2014年 / 26卷 / 05期

关键词：

Endothelin-1; Pain; Signal transduction; DORSAL-ROOT GANGLION; PERIPHERAL-NERVE INJURY; INDUCED SENSORY THRESHOLD; RAT SPINAL-CORD; A-RECEPTOR; INDUCED NOCICEPTION; NEUROPATHIC PAIN; ELDERLY-PEOPLE; CA2+ INFLUX; NEURONS;

D O I：

10.1589/jpts.26.789

中图分类号：

R49 [康复医学];

学科分类号：

100215 ;

摘要：

[Purpose] An understanding of pain is very important in the study of nanophysiotherapy. In this review, we summarize the mechanisms of endothelin-1 (ET-1)- and mitogen-activated protein kinase (MAPK)-related pain, and suggest their applications in pain physiotherapy. [Method] This review focuses on the signal transduction of pain and its mechanisms. [Results] Our reviews show that mechanisms of ET-1-and MAPK-related pain exist. [Conclusions] In this review article, we carefully discuss the signal transduction in ET-1- and MAPK-related pain with reference to pain nanophysiotherapy from the perspective of nanoparticle-associated signal transduction.

引用

页码：789 / 792

页数：4

共 47 条

[1] The contribution of capsaicin-sensitive afferents to the dorsal root ganglion sprouting of sympathetic axons after peripheral nerve injury in the rat [J].

Abbadie, C ;

Basbaum, AI .

NEUROSCIENCE LETTERS, 1998, 253 (03) :143-146

[2] Contribution of 5-and 12-lipoxygenase products to mechanical hyperalgesia induced by prostaglandin E2 and epinephrine in the rat [J].

Aley, KO ;

Levine, JD .

EXPERIMENTAL BRAIN RESEARCH, 2003, 148 (04) :482-487

[3] Specific involvement of PKC-ε in sensitization of the neuronal response to painful heat [J].

Cesare, P ;

Dekker, LV ;

Sardini, A ;

Parker, PJ ;

McNaughton, PA .

NEURON, 1999, 23 (03) :617-624

[4] Identification of MEK1 as a novel target for the treatment of neuropathic pain [J].

Ciruela, A ;

Dixon, AK ;

Bramwell, S ;

Gonzalez, MI ;

Pinnock, RD ;

Lee, K .

BRITISH JOURNAL OF PHARMACOLOGY, 2003, 138 (05) :751-756

[5]

CLERK A, 1994, J BIOL CHEM, V269, P32848

[6] Behavioral signs of acute pain produced by application of endothelin-1 to rat sciatic nerve [J].

Davar, G ;

Hans, G ;

Fareed, MU ;

Sinnott, C ;

Strichartz, G .

NEUROREPORT, 1998, 9 (10) :2279-2283

[7] Endothelin-1 and metastatic cancer pain [J].

Davar, G .

PAIN MEDICINE, 2001, 2 (01) :24-27

[8]

DOERNER D, 1988, J NEUROSCI, V8, P4069

[9] ENDOTHELINS - BIOCHEMISTRY AND PATHOPHYSIOLOGIC ACTIONS [J].

GANDHI, CR ;

BERKOWITZ, DE ;

WATKINS, WD .

ANESTHESIOLOGY, 1994, 80 (04) :892-905

[10] ENDOTHELIN-1, AN ENDOTHELIUM-DERIVED PEPTIDE, IS EXPRESSED IN NEURONS OF THE HUMAN SPINAL-CORD AND DORSAL-ROOT GANGLIA [J].

GIAID, A ;

GIBSON, SJ ;

IBRAHIM, NBN ;

LEGON, S ;

BLOOM, SR ;

YANAGISAWA, M ;

MASAKI, T ;

VARNDELL, IM ;

POLAK, JM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (19) :7634-7638

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