Integrated classification of inflammatory myopathies

被引：82

作者：

Allenbach, Y. ^{[1
,2
]}

Benveniste, O. ^{[1
,2
]}

Goebel, H-H. ^{[3
]}

Stenzel, W. ^{[3
]}

机构：

[1] Hop La Pitie Salpetriere, AP HP, Dept Internal Med & Clin Immunol, DHU I2B, Paris, France

[2] UPMC Sorbonne Univ, INSERM, U974, Paris, France

[3] Charite, Dept Neuropathol, Berlin, Germany

来源：

NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY | 2017年 / 43卷 / 01期

关键词：

autoantibodies; classification of IIMs; Morphology; Myositis; INCLUSION-BODY MYOSITIS; MONOCLONAL-ANTIBODY ANALYSIS; CYTOSOLIC 5'-NUCLEOTIDASE 1A; WORKSHOP PATHOLOGY DIAGNOSIS; MODIFIER ACTIVATING ENZYME; MEDIATED CYTO-TOXICITY; TERM-FOLLOW-UP; MONONUCLEAR-CELLS; JUVENILE DERMATOMYOSITIS; NECROTIZING MYOPATHY;

D O I：

10.1111/nan.12380

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Inflammatory myopathies comprise a multitude of diverse diseases, most often occurring in complex clinical settings. To ensure accurate diagnosis, multidisciplinary expertise is required. Here, we propose a comprehensive myositis classification that incorporates clinical, morphological and molecular data as well as autoantibody profile. This review focuses on recent advances in myositis research, in particular, the correlation between autoantibodies and morphological or clinical phenotypes that can be used as the basis for an 'integrated' classification system.

引用

页码：62 / 81

页数：20

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