Intrahepatic Cholangiocarcinoma

被引：74

作者：

Brown, Kimberly M. ^{[1
]}

Parmar, Abhishek D. ^{[1
,2
]}

Geller, David A. ^{[3
]}

机构：

[1] Univ Texas Med Branch, Dept Surg, Galveston, TX 77555 USA

[2] Univ Calif San Francisco East Bay, Dept Surg, Oakland, CA 94602 USA

[3] Univ Pittsburgh, Sch Med, Liver Canc Ctr, Pittsburgh, PA 15213 USA

来源：

SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA | 2014年 / 23卷 / 02期

关键词：

Intrahepatic cholangiocarcinoma; Peripheral cholangiocarcinoma; Cholangiocarcinoma; Bile duct neoplasms; Intrahepatic bile duct cancer; TRANSCATHETER ARTERIAL CHEMOEMBOLIZATION; PORTAL-VEIN EMBOLIZATION; LIVER-TRANSPLANTATION; PERIPHERAL CHOLANGIOCARCINOMA; BILIARY-TRACT; SINGLE-INSTITUTION; PROGNOSTIC-FACTORS; CLINICOPATHOLOGICAL FEATURES; EXTENDED HEPATECTOMY; IMPROVED SURVIVAL;

D O I：

10.1016/j.soc.2013.10.004

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Intrahepatic cholangiocarcinoma (ICC) is a rare tumor, with an increasing incidence worldwide and an overall poor prognosis. Symptoms are usually nonspecific, contributing to an advanced tumor stage at diagnosis. The staging system for ICC has recently been updated and is based on number of lesions, vascular invasion, and lymph node involvement. Complete surgical resection to negative margins remains the only potentially curable treatment for ICC. Gemcitabine-based adjuvant therapy can be offered based on limited data from patients with unresectabfe ICC. Overall 5-year survivals after resection range from 17% to 44%, with median survivals of 19 to 43 months.

引用

页码：231 / +

页数：17

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