Functionalized MoS2 Nanosheet-Based Field-Effect Biosensor for Label-Free Sensitive Detection of Cancer Marker Proteins in Solution

被引：249

作者：

Wang, Lu ^{[1
]}

Wang, Ye ^{[2
]}

Wong, Jen It ^{[2
]}

Palacios, Tomas ^{[3
]}

Kong, Jing ^{[3
]}

Yang, Hui Ying ^{[2
]}

机构：

[1] Harvard Univ, Dept Chem & Chem Biol, Cambridge, MA 02138 USA

[2] Singapore Univ Technol & Design, Singapore 138682, Singapore

[3] MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA

来源：

SMALL | 2014年 / 10卷 / 06期

关键词：

MoS2; field-effect device; biosensors; prostate-specific antigen (PSA); PROSTATE-SPECIFIC ANTIGEN; ELECTRICAL DETECTION; GRAPHENE; SENSOR; FABRICATION;

D O I：

10.1002/smll.201302081

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Label-free MoS2 nanosheet-based field-effect biosensor detects cancer marker protein Prostate Specific Antigen in real time with high sensitivity and selectivity, exhibiting great potential in point-of-care diagnostics application. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：1101 / 1105

页数：5

共 43 条

[1] Biosensors: the new wave in cancer diagnosis [J].

Bohunicky, Brian ;

Mousa, Shaker A. .

NANOTECHNOLOGY SCIENCE AND APPLICATIONS, 2011, 4 :1-10

[2] Dielectric Screening Enhanced Performance in Graphene FET [J].

Chen, Fang ;

Xia, Jilin ;

Ferry, David K. ;

Tao, Nongjian .

NANO LETTERS, 2009, 9 (07) :2571-2574

[3] Label-Free Electrical Detection of Cardiac Biomarker with Complementary Metal-Oxide Semiconductor-Compatible Silicon Nanowire Sensor Arrays [J].

Chua, Jay Huiyi ;

Chee, Ru-Ern ;

Agarwal, Ajay ;

Wong, She Mein ;

Zhang, Guo-Jun .

ANALYTICAL CHEMISTRY, 2009, 81 (15) :6266-6271

[4] High Performance Multilayer MoS2 Transistors with Scandium Contacts [J].

Das, Saptarshi ;

Chen, Hong-Yan ;

Penumatcha, Ashish Verma ;

Appenzeller, Joerg .

NANO LETTERS, 2013, 13 (01) :100-105

[5] The case for early detection [J].

Etzioni, R ;

Urban, N ;

Ramsey, S ;

McIntosh, M ;

Schwartz, S ;

Reid, B ;

Radich, J ;

Anderson, G ;

Hartwell, L .

NATURE REVIEWS CANCER, 2003, 3 (04) :243-252

[6]

Ferlay J., 2010, GLOBOCAN 2008, P29

[7] SINGLE CRYSTALS OF MOS2 SEVERAL MOLECULAR LAYERS THICK [J].

FRINDT, RF .

JOURNAL OF APPLIED PHYSICS, 1966, 37 (04) :1928-&

[8] Subthreshold Regime has the Optimal Sensitivity for Nanowire FET Biosensors [J].

Gao, Xuan P. A. ;

Zheng, Gengfeng ;

Lieber, Charles M. .

NANO LETTERS, 2010, 10 (02) :547-552

[9] The rise of graphene [J].

Geim, A. K. ;

Novoselov, K. S. .

NATURE MATERIALS, 2007, 6 (03) :183-191

[10] Fabrication of Flexible MoS2 Thin-Film Transistor Arrays for Practical Gas-Sensing Applications [J].

He, Qiyuan ;

Zeng, Zhiyuan ;

Yin, Zongyou ;

Li, Hai ;

Wu, Shixin ;

Huang, Xiao ;

Zhang, Hua .

SMALL, 2012, 8 (19) :2994-2999

← 1 2 3 4 5 →