A Comparative Pathomorphological Findings Between Leiurus abdullahbayrami and Androctonus crassicauda (Scorpion: Buthidae) Envenomation in Rabbit Animal Model

被引:0
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作者
Ozkan, Ozcan [1 ]
Alcigir, Mehmet Eray [2 ]
机构
[1] Cankiri Karatekin Univ, Cankiri, Turkey
[2] Kirikkale Univ, Fac Vet Med, Dept Pathol, Kirikkale, Turkey
关键词
Leirus abdullahbayrami; Androctonus crassicauda; Venom; Pathomorphology; Rabbit; ACUTE PULMONARY-EDEMA; IN-VIVO; TITYUS-DISCREPANS; VENOM; INTERLEUKIN-6; ANTIVENOM; AMOREUXI; CAPACITY; AUD;
D O I
暂无
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Background: The aim of study was to compare macroscopical and histopathological findings between venoms belonging to two scorpion species, Androdoctonus crassicauda, and the newly discovered Leirus abdullahbayrami. Methods: The animals used in this experimental study were fifteen New Zealand bred rabbits. Three groups were constituted as group I (L. abdullahbayrami group, n= 6), group II (A. crassicauda group, n= 6) and group III (control group, n= 3). The animals in the L. abdullahbayrami group and the A. crassicauda group were envenomed through an intravenous route. The rabbits were monitored for the first 24h following the envenomation. The animals dead within that time period were examined and all animals were sacrificed and standard necropsy process was performed at 24h. Results: The pathomorphological findings from group I were found to be more severe than those observed in group II. The venom from the newly identified L. abdullahbayrami has a greater effect than the venom from the A. crassicauda. Moreover, as this was a rabbit modeling study, the L. abdullahbayrami might pose the most serious health threat to infants in particular due to their smaller body weight. Conclusion: These findings will provide a better understanding of envenomation of human beings in terms of the possible consequences of scorpion toxication on the organs.
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页码:104 / 115
页数:12
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