Bacterial phospholipases and pathogenesis

被引:135
|
作者
Schmiel, DH
Miller, VL
机构
[1] Washington Univ, Sch Med, Dept Mol Microbiol, St Louis, MO 63110 USA
[2] Washington Univ, Sch Med, Dept Pediat, St Louis, MO 63110 USA
关键词
bacteria; phospholipase; pathogenesis;
D O I
10.1016/S1286-4579(99)00205-1
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Phospholipases are produced from a diverse group of bacterial pathogens causing very different diseases. In some cases, secreted phospholipases appear to be the major cause of pathophysiological effects. Yet in other cases, phospholipases are key virulence factors, contributing to bacterial survival or dissemination without causing tissue destruction. Perhaps the most intriguing aspect of phospholipases as virulence factors is their potential to interfere with cellular signaling cascades and to modulate the host immune response. (C) 1999 Editions scientifiques et medicales Elsevier SAS.
引用
收藏
页码:1103 / 1112
页数:10
相关论文
共 50 条
  • [31] Host and bacterial factors in listeriosis pathogenesis
    Orndorff, PE
    Hamrick, TS
    Smoak, IW
    Havell, EA
    VETERINARY MICROBIOLOGY, 2006, 114 (1-2) : 1 - 15
  • [32] The Virulent Hypothetical Proteins: The Potential Drug Target Involved in Bacterial Pathogenesis
    Naveed, Muhammad
    Makhdoom, Syeda Izma
    Abbas, Ghulam
    Safdari, Mohammadreza
    Farhadi, Amin
    Habtemariam, Solomon
    Shabbir, Muhammad Aqib
    Jabeen, Khizra
    Asif, Muhammad Farrukh
    Tehreem, Sana
    MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2022, 22 (20) : 2608 - 2623
  • [33] Pathogenicity-island-encoded regulatory RNAs regulate bacterial virulence and pathogenesis
    Zhao, Xin
    Zhang, Ying
    Huang, Xinxiang
    MICROBIAL PATHOGENESIS, 2018, 125 : 196 - 204
  • [34] The role of lipid rafts in the pathogenesis of bacterial infections
    Zaas, DW
    Duncan, M
    Wright, JR
    Abraham, SN
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2005, 1746 (03): : 305 - 313
  • [35] Bacterial Biofilms and Their Implications in Pathogenesis and Food Safety
    Bai, Xingjian
    Nakatsu, Cindy H.
    Bhunia, Arun K.
    FOODS, 2021, 10 (09)
  • [36] Bacterial-fungal interactions and their impact on microbial pathogenesis
    MacAlpine, Jessie
    Robbins, Nicole
    Cowen, Leah E.
    MOLECULAR ECOLOGY, 2023, 32 (10) : 2565 - 2581
  • [37] Siderophores: Importance in bacterial pathogenesis and applications in medicine and industry
    Khasheii, Behnoush
    Mahmoodi, Pezhman
    Mohammadzadeh, Abdolmajid
    MICROBIOLOGICAL RESEARCH, 2021, 250
  • [38] Assessment of bacterial pathogenesis by analysis of gene expression in the host
    Mahan, MJ
    Heithoff, DM
    Sinsheimer, RL
    Low, DA
    ANNUAL REVIEW OF GENETICS, 2000, 34 : 139 - 164
  • [39] The extracytoplasmic function sigma factors: role in bacterial pathogenesis
    Bashyam, Murali D.
    Hasnain, Seyed E.
    INFECTION GENETICS AND EVOLUTION, 2004, 4 (04) : 301 - 308
  • [40] Bacterial Biopolymer: Its Role in Pathogenesis to Effective Biomaterials
    Ghosh, Sreejita
    Lahiri, Dibyajit
    Nag, Moupriya
    Dey, Ankita
    Sarkar, Tanmay
    Pathak, Sushil Kumar
    Atan Edinur, Hisham
    Pati, Siddhartha
    Ray, Rina Rani
    POLYMERS, 2021, 13 (08)