Bacterial phospholipases and pathogenesis

被引:135
|
作者
Schmiel, DH
Miller, VL
机构
[1] Washington Univ, Sch Med, Dept Mol Microbiol, St Louis, MO 63110 USA
[2] Washington Univ, Sch Med, Dept Pediat, St Louis, MO 63110 USA
关键词
bacteria; phospholipase; pathogenesis;
D O I
10.1016/S1286-4579(99)00205-1
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Phospholipases are produced from a diverse group of bacterial pathogens causing very different diseases. In some cases, secreted phospholipases appear to be the major cause of pathophysiological effects. Yet in other cases, phospholipases are key virulence factors, contributing to bacterial survival or dissemination without causing tissue destruction. Perhaps the most intriguing aspect of phospholipases as virulence factors is their potential to interfere with cellular signaling cascades and to modulate the host immune response. (C) 1999 Editions scientifiques et medicales Elsevier SAS.
引用
收藏
页码:1103 / 1112
页数:10
相关论文
共 50 条
  • [11] Pathogenesis of bacterial meningitis
    Adam R.
    Schroten H.
    Monatsschrift Kinderheilkunde, 2004, 152 (4) : 362 - 370
  • [12] Host Antimicrobial Peptides in Bacterial Homeostasis and Pathogenesis of Disease
    Heimlich, Derek R.
    Harrison, Alistair
    Mason, Kevin M.
    ANTIBIOTICS-BASEL, 2014, 3 (04): : 645 - 676
  • [13] Pathogenesis-Associated Bacterial Amyloids: The Network of Interactions
    Fayoud, Haidar
    Belousov, Mikhail V.
    Antonets, Kirill S.
    Nizhnikov, Anton A.
    BIOCHEMISTRY-MOSCOW, 2024, 89 (12-13) : 2107 - 2132
  • [14] Advances in the Study of Bacterial Toxins, Their Roles and Mechanisms in Pathogenesis
    Ghazaei, Ciamak
    MALAYSIAN JOURNAL OF MEDICAL SCIENCES, 2022, 29 (01): : 4 - 17
  • [15] New roles for glutathione: Modulators of bacterial virulence and pathogenesis
    Ku, Joanne Wei Kay
    Gan, Yunn-Hwen
    REDOX BIOLOGY, 2021, 44
  • [16] Role of Selenoproteins in Bacterial Pathogenesis
    Sarah E. Sumner
    Rachel L. Markley
    Girish S. Kirimanjeswara
    Biological Trace Element Research, 2019, 192 : 69 - 82
  • [17] Bacterial infection and the pathogenesis of COPD
    Sethi, S
    CHEST, 2000, 117 (05) : 286S - 291S
  • [18] The pathogenesis of gastrointestinal bacterial overgrowth
    Husebye, E
    CHEMOTHERAPY, 2005, 51 : 1 - 22
  • [19] Role of Selenoproteins in Bacterial Pathogenesis
    Sumner, Sarah E.
    Markley, Rachel L.
    Kirimanjeswara, Girish S.
    BIOLOGICAL TRACE ELEMENT RESEARCH, 2019, 192 (01) : 69 - 82
  • [20] How microbiological tests reflect bacterial pathogenesis and host adaptation
    Luisella Spiga
    Angel G. Jimenez
    Renato L. Santos
    Sebastian E. Winter
    Brazilian Journal of Microbiology, 2021, 52 : 1745 - 1753