First Gene Cassettes of Integrons as Targets in Finding Adaptive Genes in Metagenomes

被引:12
|
作者
Huang, Lionel [1 ]
Cagnon, Christine [1 ]
Caumette, Pierre [1 ]
Duran, Robert [1 ]
机构
[1] Univ Pau & Pays Adour, CNRS, UMR 5254, Equipe Environm & Microbiol,IPREM,IBEAS, F-64013 Pau, France
关键词
ANTIBIOTIC-RESISTANCE GENES; ENVIRONMENTAL DNA; CLASS-1; INTEGRONS; VIBRIO-CHOLERAE; RECOMBINATION; IDENTIFICATION; DIVERSITY; EVOLUTION; RECOVERY; BACTERIA;
D O I
10.1128/AEM.02394-08
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The first gene cassettes of integrons are involved in the last adaptation response to changing conditions and are also the most expressed. We propose a rapid method for the selection of clones carrying an integron first gene cassette that is useful for finding adaptive genes in environmental metagenomic libraries.
引用
收藏
页码:3823 / 3825
页数:3
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