Light-Controlled Chemical Reactions and Their Applications in Biological Systems

被引:2
|
作者
Lee, Jeeyeon [1 ]
机构
[1] Seoul Natl Univ, Coll Pharm, Seoul, South Korea
基金
新加坡国家研究基金会;
关键词
azobenzene; fluorescence; green fluorescent protein; isomerization; photochemistry; GREEN FLUORESCENT PROTEIN; EXCITED-STATE DYNAMICS; GFP-CHROMOPHORE ANALOGS; ION CHANNELS; STRUCTURAL BASIS; OPTICAL CONTROL; AZOBENZENE PHOTOSWITCHES; BENZYLIDENE-OXAZOLONES; GENE-EXPRESSION; PHOTO-CONTROL;
D O I
10.1002/ajoc.201402054
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Light has long been used as an external signal to control biological systems. The ability to control chemical reactions with a light stimulus has led to advances in the use of optical techniques for the precise control of biological systems. In particular, light can be used to reversibly control biological processes via photoisomerization of light-responsive molecules. This Focus Review discusses recent developments of novel light-controlled compounds including photoresponsive drugs, red light-shifted azobenzene photoswitches, and synthetic chromophores of fluorescent proteins with new spectroscopic characteristics.
引用
收藏
页码:830 / 837
页数:8
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