Cost-utility Analysis for Recurrent Lumbar Disc Herniation Conservative Treatment Versus Discectomy Versus Discectomy With Fusion

被引:14
作者
Selva-Sevilla, Carmen [1 ]
Ferrara, Paula [2 ]
Geroninio-Pardo, Manuel [3 ]
机构
[1] Univ Castilla La Mancha, Fac Econ Sci Albacete, Dept Appl Econ, Albacete, Spain
[2] Univ Hosp Complex Albacete, Dept Neurosurg, Albacete, Spain
[3] Univ Hosp Complex Albacete, Dept Anesthesiol, Albacete, Spain
来源
CLINICAL SPINE SURGERY | 2019年 / 32卷 / 05期
关键词
lumbar disc herniation recurrence; conservative treatment; discectomy; spinal fusion; cost-utility; Short-Form; 36; EuroQol-5D; Oswestry Disability Index; quality-adjusted life years; OSWESTRY DISABILITY INDEX; NUMERIC RATING-SCALES; DEGENERATIVE-SPONDYLOLISTHESIS; REPEAT DISKECTOMY; SPINAL-STENOSIS; OUTCOMES; CARE; SURGERY; EQ-5D; BACK;
D O I
10.1097/BSD.0000000000000797
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Study Design: This study was an ambispective long-term costutility analysis with retrospective chart review and included the prospective completion of health questionnaires by patients. Objective: This was a cost-utility analysis, comparing conservative treatment, discectomy, and discectomy with spinal fusion for patients with recurrent lumbar disc herniation after a previous discectomy. Summary of Background Data: Lumbar disc herniation is an important health problem, with recurrence rates ranging from 5% to 15%. Management of recurrences is controversial due to a lack of high-level evidence. Cost-effectiveness analyses are useful when making clinical decisions. There are economic assessments for first herniations, but not in the context of recurrent lumbar disc herniations. Materials and Methods: Fifty patients with disc herniation recurrence underwent conservative treatment (n= 11), discectomy (n= 20), or discectomy with fusion (n= 19), and they completed the Short-Form 36, EuroQol-5D, and Oswestry Disability Index. Baseline case quality-adjusted life year (QALY) values, cost-utility ratios, and incremental cost-utility ratios were calculated on the basis of the SF-36. Direct health costs were calculated by applying the health care system perspective. Both QALY and costs were discounted at a rate of 3%. One-way sensitivity analyses were conducted for uncertainty variables, such as other health surveys or 2-year follow-up. Results: Cost-utility analysis of conservative treatment versus discectomy showed that the former is dominant, mainly because it is significantly more economical ((sic) 904 vs. (sic)6718, P< 0.001), while health results were very similar (3.48 vs. 3.18, P= 0.887). Cost-utility analysis of discectomy versus discectomy with fusion revealed that discectomy is dominant, showing a trend to be both more economical ((sic) 6718 vs. (sic) 9364, P= 0.054) and more effective (3.18 vs. 1.92 QALY, P= 0.061). Conclusions: This cost-utility analysis showed that conservative treatment is more cost-effective than discectomy in patients with lumbar disc herniation recurrence. In cases of recurrence in which conservative treatment is not feasible, and another surgery must be performed for the patient, discectomy is a more costeffective surgical alternative than discectomy with fusion. Level of Evidence: Level II.
引用
收藏
页码:E228 / E234
页数:7
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