Post-transplant lymphoproliferative disorders: T-cell lymphoma following cardiac transplant

被引:16
|
作者
Haldas, J [1 ]
Wei, WB [1 ]
Lazarchick, J [1 ]
机构
[1] Med Univ S Carolina, Div Haematol & Oncol, Dept Med, Charleston, SC 29403 USA
关键词
PTLD; heart transplantation; T-cell lymphoma; immunosuppression; Epstein-Barr virus;
D O I
10.1080/10428190290006332
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Post-transplant lymphoproliferative disorders (PTLD) are a frequently fatal complication occurring after transplant. The majority of cases are of B-cell origin but a smaller percentage of cases are of T-cell origin. The etiology of these disorders is unclear, however, EBV (Epstein-Barr virus) in the context of immunosupperssion is thought to play a role, particularly in B-cell PTLD. We report a case of T-cell PTLD limited to the bone marrow occurring eight years post-cardiac transplantation and review the literature on T-cell PTLD after heart transplant.
引用
收藏
页码:447 / 450
页数:4
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