Cancer incidence in people with affective disorder: nationwide cohort study in Taiwan, 1997-2010

被引：27

作者：

Hung, Yen-Ni ^{[1
,2
,3
,4
]}

Yang, Shu-Yu ^{[5
,6
]}

Huang, Ming-Chyi ^{[5
,7
]}

Lung, For-Wey ^{[5
]}

Lin, Shih-Ku ^{[5
,7
]}

Chen, Kuan-Yu ^{[5
]}

Kuo, Chian-Jue ^{[5
,7
,8
]}

Chen, Ying-Yeh ^{[5
,9
,10
]}

机构：

[1] Taipei Med Univ, Sch Gerontol Hlth Management, Coll Nursing, Taipei, Taiwan

[2] Taipei Med Univ, Master Program Long Term Care, Coll Nursing, Taipei, Taiwan

[3] Natl Yang Ming Univ, Dept Nursing, Sch Nursing, Taipei 112, Taiwan

[4] Taipei City Hosp, Dept Educ & Res, Taipei, Taiwan

[5] Taipei City Hosp, Taipei City Psychiat Ctr, Taipei, Taiwan

[6] Kaohsiung Med Univ, Grad Inst Clin Pharm, Coll Pharm, Kaohsiung, Taiwan

[7] Taipei Med Univ, Sch Med, Dept Psychiat, Taipei, Taiwan

[8] Taipei Med Univ Hosp, Psychiat Res Ctr, Taipei, Taiwan

[9] Natl Yang Ming Univ, Inst Publ Hlth, Taipei 112, Taiwan

[10] Natl Yang Ming Univ, Dept Publ Hlth, Taipei 112, Taiwan

来源：

BRITISH JOURNAL OF PSYCHIATRY | 2014年 / 205卷 / 03期

关键词：

BIPOLAR DISORDER; SUBSTANCE USE; RISK; SCHIZOPHRENIA; DEPRESSION; ALCOHOL; COMORBIDITY; SMOKING; TOBACCO; SAMPLE;

D O I：

10.1192/bjp.bp.114.144741

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Background Cancer is a serious public health problem worldwide, and its relationship with affective disorders is not clear. Aims To investigate alcohol- and tobacco-related cancer risk among patients with affective disorders in a large Taiwanese cohort. Method Records of newly admitted patients with affective disorders from January 1997 through December 2002 were retrieved from the Psychiatric Inpatient Medical Claims database in Taiwan. Cancers were stratified by site and grouped into tobacco- or alcohol-related cancers. Standardised incidence ratios (SIRS) were calculated to compare the risk of cancer between those with affective disorders and the general population. Results Some 10 207 patients with bipolar disorder and 9826 with major depression were included. The risk of cancer was higher in patients with major depression (SIR=2.01, 95% CI 1.85-2.19) than in those with bipolar disorder (SIR 1.39, 95% CI 1.26-1.53). The elevated cancer risk among individuals ever admitted to hospital for affective disorders was more pronounced in tobacco- and/or alcohol-related cancers. Conclusions Elevated cancer risk was found in patients who had received in-patient care for affective disorders. They require holistic approaches to lifestyle behaviours and associated cancer risks.

引用

页码：183 / 188

页数：6

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