Synthesis of 5-Aryl-4-aroyl-3-hydroxy-1-cyanomethyl-3-pyrrolin-2-ones

被引：11

作者：

Gein, V. L. ^{[1
]}

Buldakova, E. A. ^{[1
]}

Korol, A. N. ^{[1
]}

Veikhman, G. A. ^{[1
]}

Dmitriev, M. V. ^{[2
]}

机构：

[1] Perm State Pharmaceut Acad, Ul Polevaya 2, Perm 614990, Russia

[2] Perm State Natl Res Univ, Perm, Russia

来源：

RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2018年 / 88卷 / 05期

关键词：

5-aryl-4-aroyl-3-hydroxy-1-cyanomethyl-3-pyrrolin-2-ones; 2-aminoacetonitrile sulfate; tetrahydropyrrole-2,3-diones; three-component reactions;

D O I：

10.1134/S1070363218050110

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

5-Aryl-4-aroyl-3-hydroxy-1-cyanomethyl-3-pyrrolin-2-ones were synthesized by a three-component reaction of methyl aroylpyruvate with a mixture of aromatic aldehyde and 2-aminoacetonitrile sulfate in glacial acetic acid in the presence of anhydrous sodium acetate.

引用

页码：908 / 911

页数：4

共 9 条

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