Fourteen Years of Severe Arthralgia in a Man without Gastrointestinal Symptoms: Atypical Whipple's Disease

被引:5
作者
Mancini, Fabiola [1 ]
Sbaragli, Serena [2 ]
Colivicchi, Gilberto [2 ]
Cassone, Antonio [1 ]
Ciervo, Alessandra [1 ]
机构
[1] Ist Super Sanita, Dept Infect Parasit & Immune Mediated Dis, I-00161 Rome, Italy
[2] Ist Fiorentino Cura & Assistenza, Dept Internal Med, Florence, Italy
关键词
TROPHERYMA-WHIPPELII; INFECTIVE ENDOCARDITIS; BONE DESTRUCTION; INVOLVEMENT; ARTHRITIS; MANIFESTATIONS; SUSCEPTIBILITY; DIAGNOSIS; PATIENT; SYSTEM;
D O I
10.1128/JCM.01833-08
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We report here the case of Whipple's disease in a 60-year-old man with severe arthralgia and systemic disorders but without gastrointestinal manifestations. The patient had different clinical diagnoses over a period of 14 years. We identified Tropheryma whipplei by real-time PCR. Molecular typing was also performed by sequencing the 16S-23S rRNA intergenic spacer region and domain III of the 23S rRNA gene.
引用
收藏
页码:492 / 495
页数:4
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