共 119 条
A post-genomic approach to understanding sphingolipid metabolism in Arabidopsis thaliana
被引:126
作者:

Dunn, TM
论文数: 0 引用数: 0
h-index: 0
机构: Rothamsted Res, Harpenden AL5 2JQ, Herts, England

Lynch, DV
论文数: 0 引用数: 0
h-index: 0
机构: Rothamsted Res, Harpenden AL5 2JQ, Herts, England

Michaelson, LV
论文数: 0 引用数: 0
h-index: 0
机构: Rothamsted Res, Harpenden AL5 2JQ, Herts, England

Napier, JA
论文数: 0 引用数: 0
h-index: 0
机构:
Rothamsted Res, Harpenden AL5 2JQ, Herts, England Rothamsted Res, Harpenden AL5 2JQ, Herts, England
机构:
[1] Rothamsted Res, Harpenden AL5 2JQ, Herts, England
[2] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA
[3] Williams Coll, Williamstown, MA 01267 USA
基金:
英国生物技术与生命科学研究理事会;
美国国家科学基金会;
关键词:
Arabidopsis thatiana;
ceramide;
desaturase;
lipid metabolism;
long chain base;
post-genomics;
Saccharomyces cerevisiae;
signalling;
sphingolipid;
D O I:
10.1093/aob/mch071
中图分类号:
Q94 [植物学];
学科分类号:
071001 ;
摘要:
Aims To highlight the importance of sphingolipids and their metabolites in plant biology. Scope The completion of the arabidopsis genome provides a platform for the identification and functional characterization of genes involved in sphingolipid biosynthesis. Using the yeast Saccharomyces cerevisiae as an experimental model, this review annotates arabidopsis open reading frames likely to be involved in sphingolipid metabolism. A number of these open reading frames have already been subject to functional characterization, though the majority still awaits investigation. Plant-specific aspects of sphingolipid biology (such as enhanced long chain base heterogeneity) are considered in the context of the emerging roles for these lipids in plant form and function. Conclusions Arabidopsis provides an excellent genetic and post-genomic model for the characterization of the roles of sphingolipids in higher plants. (C) 2004 Annals of Botany Company.
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页码:483 / 497
页数:15
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共 119 条
- [11] A longevity assurance gene homolog of tomato mediates resistance to Alternaria alternata f. sp lycopersici toxins and fumonisin B1[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (09) : 4961 - 4966Brandwagt, BF论文数: 0 引用数: 0 h-index: 0机构: Free Univ Amsterdam, Inst Mol Biol Sci, Bioctr Amsterdam, Dept Genet, NL-1081 HV Amsterdam, Netherlands Free Univ Amsterdam, Inst Mol Biol Sci, Bioctr Amsterdam, Dept Genet, NL-1081 HV Amsterdam, NetherlandsMesbah, LA论文数: 0 引用数: 0 h-index: 0机构: Free Univ Amsterdam, Inst Mol Biol Sci, Bioctr Amsterdam, Dept Genet, NL-1081 HV Amsterdam, Netherlands Free Univ Amsterdam, Inst Mol Biol Sci, Bioctr Amsterdam, Dept Genet, NL-1081 HV Amsterdam, NetherlandsTakken, FLW论文数: 0 引用数: 0 h-index: 0机构: Free Univ Amsterdam, Inst Mol Biol Sci, Bioctr Amsterdam, Dept Genet, NL-1081 HV Amsterdam, Netherlands Free Univ Amsterdam, Inst Mol Biol Sci, Bioctr Amsterdam, Dept Genet, NL-1081 HV Amsterdam, NetherlandsLaurent, PL论文数: 0 引用数: 0 h-index: 0机构: Free Univ Amsterdam, Inst Mol Biol Sci, Bioctr Amsterdam, Dept Genet, NL-1081 HV Amsterdam, Netherlands Free Univ Amsterdam, Inst Mol Biol Sci, Bioctr Amsterdam, Dept Genet, NL-1081 HV Amsterdam, NetherlandsKneppers, TJA论文数: 0 引用数: 0 h-index: 0机构: Free Univ Amsterdam, Inst Mol Biol Sci, Bioctr Amsterdam, Dept Genet, NL-1081 HV Amsterdam, Netherlands Free Univ Amsterdam, Inst Mol Biol Sci, Bioctr Amsterdam, Dept Genet, NL-1081 HV Amsterdam, NetherlandsHille, J论文数: 0 引用数: 0 h-index: 0机构: Free Univ Amsterdam, Inst Mol Biol Sci, Bioctr Amsterdam, Dept Genet, NL-1081 HV Amsterdam, Netherlands Free Univ Amsterdam, Inst Mol Biol Sci, Bioctr Amsterdam, Dept Genet, NL-1081 HV Amsterdam, NetherlandsNijkamp, HJJ论文数: 0 引用数: 0 h-index: 0机构: Free Univ Amsterdam, Inst Mol Biol Sci, Bioctr Amsterdam, Dept Genet, NL-1081 HV Amsterdam, Netherlands Free Univ Amsterdam, Inst Mol Biol Sci, Bioctr Amsterdam, Dept Genet, NL-1081 HV Amsterdam, Netherlands
- [12] Knockout of Arabidopsis ACCELERATED-CELL-DEATH11 encoding a sphingosine transfer protein causes activation of programmed cell death and defense[J]. GENES & DEVELOPMENT, 2002, 16 (04) : 490 - 502Brodersen, P论文数: 0 引用数: 0 h-index: 0机构: Univ Copenhagen, Inst Mol Biol, DK-1353 Copenhagen K, DenmarkPetersen, M论文数: 0 引用数: 0 h-index: 0机构: Univ Copenhagen, Inst Mol Biol, DK-1353 Copenhagen K, DenmarkPike, HM论文数: 0 引用数: 0 h-index: 0机构: Univ Copenhagen, Inst Mol Biol, DK-1353 Copenhagen K, DenmarkOlszak, B论文数: 0 引用数: 0 h-index: 0机构: Univ Copenhagen, Inst Mol Biol, DK-1353 Copenhagen K, DenmarkSkov, S论文数: 0 引用数: 0 h-index: 0机构: Univ Copenhagen, Inst Mol Biol, DK-1353 Copenhagen K, DenmarkOdum, N论文数: 0 引用数: 0 h-index: 0机构: Univ Copenhagen, Inst Mol Biol, DK-1353 Copenhagen K, DenmarkJorgensen, LB论文数: 0 引用数: 0 h-index: 0机构: Univ Copenhagen, Inst Mol Biol, DK-1353 Copenhagen K, DenmarkBrown, RE论文数: 0 引用数: 0 h-index: 0机构: Univ Copenhagen, Inst Mol Biol, DK-1353 Copenhagen K, DenmarkMundy, J论文数: 0 引用数: 0 h-index: 0机构: Univ Copenhagen, Inst Mol Biol, DK-1353 Copenhagen K, Denmark Univ Copenhagen, Inst Mol Biol, DK-1353 Copenhagen K, Denmark
- [13] Complex sphingolipid synthesis in plants: characterization of inositolphosphorylceramide synthase activity in bean microsomes[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2003, 417 (02) : 219 - 226Bromley, PE论文数: 0 引用数: 0 h-index: 0机构: Williams Coll, Dept Biol, Williamstown, MA 01267 USA Williams Coll, Dept Biol, Williamstown, MA 01267 USALi, YNO论文数: 0 引用数: 0 h-index: 0机构: Williams Coll, Dept Biol, Williamstown, MA 01267 USA Williams Coll, Dept Biol, Williamstown, MA 01267 USAMurphy, SM论文数: 0 引用数: 0 h-index: 0机构: Williams Coll, Dept Biol, Williamstown, MA 01267 USA Williams Coll, Dept Biol, Williamstown, MA 01267 USASumner, CM论文数: 0 引用数: 0 h-index: 0机构: Williams Coll, Dept Biol, Williamstown, MA 01267 USA Williams Coll, Dept Biol, Williamstown, MA 01267 USALynch, DV论文数: 0 引用数: 0 h-index: 0机构: Williams Coll, Dept Biol, Williamstown, MA 01267 USA Williams Coll, Dept Biol, Williamstown, MA 01267 USA
- [14] Substrate-dependent mutant complementation to select fatty acid desaturase variants for metabolic engineering of plant seed oils[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (22) : 12350 - 12355Cahoon, EB论文数: 0 引用数: 0 h-index: 0机构: Brookhaven Natl Lab, Dept Biol, Upton, NY 11973 USA Brookhaven Natl Lab, Dept Biol, Upton, NY 11973 USAShanklin, J论文数: 0 引用数: 0 h-index: 0机构: Brookhaven Natl Lab, Dept Biol, Upton, NY 11973 USA Brookhaven Natl Lab, Dept Biol, Upton, NY 11973 USA
- [15] Transgenic production of epoxy fatty acids by expression of a cytochrome P450 enzyme from Euphorbia lagascae seed[J]. PLANT PHYSIOLOGY, 2002, 128 (02) : 615 - 624Cahoon, EB论文数: 0 引用数: 0 h-index: 0机构: DuPont Crop Genet, Expt Stn, Wilmington, DE 19880 USA DuPont Crop Genet, Expt Stn, Wilmington, DE 19880 USARipp, KG论文数: 0 引用数: 0 h-index: 0机构: DuPont Crop Genet, Expt Stn, Wilmington, DE 19880 USA DuPont Crop Genet, Expt Stn, Wilmington, DE 19880 USAHall, SE论文数: 0 引用数: 0 h-index: 0机构: DuPont Crop Genet, Expt Stn, Wilmington, DE 19880 USA DuPont Crop Genet, Expt Stn, Wilmington, DE 19880 USAMcGonigle, B论文数: 0 引用数: 0 h-index: 0机构: DuPont Crop Genet, Expt Stn, Wilmington, DE 19880 USA DuPont Crop Genet, Expt Stn, Wilmington, DE 19880 USA
- [16] Formation of conjugated Δ8,Δ10-double bonds by Δ12-oleic-acid desaturase-related enzymes -: Biosynthetic origin of calendic acid[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (04) : 2637 - 2643Cahoon, EB论文数: 0 引用数: 0 h-index: 0机构: DuPont Nutr & Hlth, Expt Stn, Wilmington, DE 19880 USA DuPont Nutr & Hlth, Expt Stn, Wilmington, DE 19880 USARipp, KG论文数: 0 引用数: 0 h-index: 0机构: DuPont Nutr & Hlth, Expt Stn, Wilmington, DE 19880 USA DuPont Nutr & Hlth, Expt Stn, Wilmington, DE 19880 USAHall, SE论文数: 0 引用数: 0 h-index: 0机构: DuPont Nutr & Hlth, Expt Stn, Wilmington, DE 19880 USA DuPont Nutr & Hlth, Expt Stn, Wilmington, DE 19880 USAKinney, AJ论文数: 0 引用数: 0 h-index: 0机构: DuPont Nutr & Hlth, Expt Stn, Wilmington, DE 19880 USA DuPont Nutr & Hlth, Expt Stn, Wilmington, DE 19880 USA
- [17] Sphingolipid signalling in Arabidopsis guard cells involves heterotrimeric G proteins[J]. NATURE, 2003, 423 (6940) : 651 - 654Coursol, S论文数: 0 引用数: 0 h-index: 0机构: Penn State Univ, Dept Biol, Mueller Lab 208, University Pk, PA 16802 USAFan, LM论文数: 0 引用数: 0 h-index: 0机构: Penn State Univ, Dept Biol, Mueller Lab 208, University Pk, PA 16802 USALe Stunff, H论文数: 0 引用数: 0 h-index: 0机构: Penn State Univ, Dept Biol, Mueller Lab 208, University Pk, PA 16802 USASpiegel, S论文数: 0 引用数: 0 h-index: 0机构: Penn State Univ, Dept Biol, Mueller Lab 208, University Pk, PA 16802 USAGilroy, S论文数: 0 引用数: 0 h-index: 0机构: Penn State Univ, Dept Biol, Mueller Lab 208, University Pk, PA 16802 USAAssmann, SM论文数: 0 引用数: 0 h-index: 0机构: Penn State Univ, Dept Biol, Mueller Lab 208, University Pk, PA 16802 USA Penn State Univ, Dept Biol, Mueller Lab 208, University Pk, PA 16802 USA
- [18] Characterization of sphinganine kinase activity in corn shoot microsomes[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1997, 337 (02) : 284 - 290Crowther, GJ论文数: 0 引用数: 0 h-index: 0机构: WILLIAMS COLL,DEPT BIOL,WILLIAMSTOWN,MA 01267 WILLIAMS COLL,DEPT BIOL,WILLIAMSTOWN,MA 01267Lynch, DV论文数: 0 引用数: 0 h-index: 0机构: WILLIAMS COLL,DEPT BIOL,WILLIAMSTOWN,MA 01267 WILLIAMS COLL,DEPT BIOL,WILLIAMSTOWN,MA 01267
- [19] REGULATION OF TRANSPLASMALEMMA ELECTRON-TRANSPORT IN OAT MESOPHYLL-CELLS BY SPHINGOID BASES AND BLUE-LIGHT[J]. PLANT PHYSIOLOGY, 1989, 89 (04) : 1345 - 1350DHARMAWARDHANE, S论文数: 0 引用数: 0 h-index: 0机构: UNIV MASSACHUSETTS,DEPT BOT,AMHERST,MA 01003 UNIV MASSACHUSETTS,DEPT BOT,AMHERST,MA 01003RUBINSTEIN, B论文数: 0 引用数: 0 h-index: 0机构: UNIV MASSACHUSETTS,DEPT BOT,AMHERST,MA 01003 UNIV MASSACHUSETTS,DEPT BOT,AMHERST,MA 01003STERN, AI论文数: 0 引用数: 0 h-index: 0机构: UNIV MASSACHUSETTS,DEPT BOT,AMHERST,MA 01003 UNIV MASSACHUSETTS,DEPT BOT,AMHERST,MA 01003
- [20] Synthesis of mannose-(inositol-P)(2)-ceramide, the major sphingolipid in Saccharomyces cerevisiae, requires the IPT1 (YDR072c) gene[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (47) : 29620 - 29625Dickson, RC论文数: 0 引用数: 0 h-index: 0机构: UNIV KENTUCKY, MED CTR, LUCILLE P MARKEY CANC CTR, LEXINGTON, KY 40536 USA UNIV KENTUCKY, MED CTR, LUCILLE P MARKEY CANC CTR, LEXINGTON, KY 40536 USANagiec, EE论文数: 0 引用数: 0 h-index: 0机构: UNIV KENTUCKY, MED CTR, LUCILLE P MARKEY CANC CTR, LEXINGTON, KY 40536 USA UNIV KENTUCKY, MED CTR, LUCILLE P MARKEY CANC CTR, LEXINGTON, KY 40536 USAWells, GB论文数: 0 引用数: 0 h-index: 0机构: UNIV KENTUCKY, MED CTR, LUCILLE P MARKEY CANC CTR, LEXINGTON, KY 40536 USA UNIV KENTUCKY, MED CTR, LUCILLE P MARKEY CANC CTR, LEXINGTON, KY 40536 USANagiec, MM论文数: 0 引用数: 0 h-index: 0机构: UNIV KENTUCKY, MED CTR, LUCILLE P MARKEY CANC CTR, LEXINGTON, KY 40536 USA UNIV KENTUCKY, MED CTR, LUCILLE P MARKEY CANC CTR, LEXINGTON, KY 40536 USALester, RL论文数: 0 引用数: 0 h-index: 0机构: UNIV KENTUCKY, MED CTR, LUCILLE P MARKEY CANC CTR, LEXINGTON, KY 40536 USA UNIV KENTUCKY, MED CTR, LUCILLE P MARKEY CANC CTR, LEXINGTON, KY 40536 USA