Effect of cinnamic acid on phase transition and pH-dependent release property of monoolein cubic phase

被引：5

作者：

Zhang, Hong

Kim, Jin-Chul ^{[1
]}

机构：

[1] Kangwon Natl Univ, Coll Biomed Sci, Chunchon 200701, Kangwon Do, South Korea

来源：

JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY | 2015年 / 32卷

基金：

新加坡国家研究基金会;

关键词：

Monoolein; Cubic phase; Cinnamic acid; Phase transition temperature; pH-dependent release; DRUG-DELIVERY SYSTEMS; NANOPARTICLES; BEHAVIOR;

D O I：

10.1016/j.jiec.2015.09.014

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Monoolein (MO) cubic phases containing cinnamic acid (CA) were prepared by hydrating the mixture melts of MO and CA with buffer solutions. The release degree of methylene blue (MB, a cationic dye) from the cubic phases was higher when the pH value of release medium was lower and was suppressed more when the CA content was higher. On the contrary, the release degree of amaranth (AM, an anionic dye) from the cubic phases was higher at a higher pH value and at all the pH values tested was little affected by the CA content. (C) 2015 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights

引用

页码：319 / 326

页数：8

共 26 条

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