Epidemiology of neurological diseases in older adults

被引:87
作者
Dumurgier, J. [1 ,2 ]
Tzourio, C. [3 ]
机构
[1] Univ Paris, Cognit Neurol Ctr, St Louis Lariboisiere Fernand Widal Hosp, AP HP, Paris, France
[2] Univ Paris, Epidemiol Ageing & Neurodegenerat Dis, Inserm U1153, Paris, France
[3] Univ Bordeaux, Bordeaux Populat Hlth Res Ctr, UMR1219, Bordeaux, France
关键词
Epidemiology; Older adults; Alzheimer's disease; Aging; Neurological diseases; MULTIPLE SYSTEM ATROPHY; LEWY BODY PATHOLOGY; PARKINSONS-DISEASE; ALZHEIMERS-DISEASE; ISCHEMIC-STROKE; NATURAL-HISTORY; RISK-FACTOR; DEMENTIA; PREVALENCE; AGE;
D O I
10.1016/j.neurol.2020.01.356
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Neurological diseases refer to the diseases that target the nervous system (brain, spine or nerves). They are the second leading cause of death, and the first cause of severe long-term disability in the world. The prevalence of most neurological diseases increases sharply with age, and age also modulates the impact of risk factors, clinical presentation and the natural course of these diseases. Longitudinal population-based studies provide useful insights for a better understanding of the specificities of neurological diseases in older adults by assessment of a wide range of risk factors. Rapid population aging, especially in low-income countries, presents challenges in terms of health and social care. A multidisciplinary approach is necessary to find solutions to tackle the burden of neurological diseases in older adults. (C) 2020 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:642 / 648
页数:7
相关论文
共 99 条
[1]   The effect of age of onset of PD on risk of dementia [J].
Aarsland, D. ;
Kvaloy, J. T. ;
Andersen, K. ;
Larsen, J. P. ;
Tang, M. X. ;
Lolk, A. ;
Kragh-Sorensen, P. ;
Marder, K. .
JOURNAL OF NEUROLOGY, 2007, 254 (01) :38-45
[2]   Association between systolic blood pressure and dementia in the Whitehall II cohort study: role of age, duration, and threshold used to define hypertension [J].
Abell, Jessica G. ;
Kivimaki, Mika ;
Dugravot, Aline ;
Tabak, Adam G. ;
Fayosse, Aurore ;
Shipley, Martin ;
Sabia, Severine ;
Singh-Manoux, Archana .
EUROPEAN HEART JOURNAL, 2018, 39 (33) :3119-3125
[3]   Epilepsy in the elderly: Special considerations and challenges [J].
Acharya, Jayant N. ;
Acharya, Vinita J. .
ANNALS OF INDIAN ACADEMY OF NEUROLOGY, 2014, 17 :S18-S26
[4]   CLASSIFICATION OF SUBTYPE OF ACUTE ISCHEMIC STROKE - DEFINITIONS FOR USE IN A MULTICENTER CLINICAL-TRIAL [J].
ADAMS, HP ;
BENDIXEN, BH ;
KAPPELLE, LJ ;
BILLER, J ;
LOVE, BB ;
GORDON, DL ;
MARSH, EE ;
KASE, CS ;
WOLF, PA ;
BABIKIAN, VL ;
LICATAGEHR, EE ;
ALLEN, N ;
BRASS, LM ;
FAYAD, PB ;
PAVALKIS, FJ ;
WEINBERGER, JM ;
TUHRIM, S ;
RUDOLPH, SH ;
HOROWITZ, DR ;
BITTON, A ;
MOHR, JP ;
SACCO, RL ;
CLAVIJO, M ;
ROSENBAUM, DM ;
SPARR, SA ;
KATZ, P ;
KLONOWSKI, E ;
CULEBRAS, A ;
CAREY, G ;
MARTIR, NI ;
FICARRA, C ;
HOGAN, EL ;
CARTER, T ;
GURECKI, P ;
MUNTZ, BK ;
RAMIREZLASSEPAS, M ;
TULLOCH, JW ;
QUINONES, MR ;
MENDEZ, M ;
ZHANG, SM ;
ALA, T ;
JOHNSTON, KC ;
ANDERSON, DC ;
TARREL, RM ;
NANCE, MA ;
BUDLIE, SR ;
DIERICH, M ;
HELGASON, CM ;
HIER, DB ;
SHAPIRO, RA .
STROKE, 1993, 24 (01) :35-41
[5]   Parkinson's disease pathogenesis, evolution and alternative pathways: A review [J].
Alexoudi, A. ;
Alexoudi, I. ;
Gatzonis, S. .
REVUE NEUROLOGIQUE, 2018, 174 (10) :699-704
[6]   Treatment of hypertension in patients 80 years of age or older [J].
Beckett, Nigel S. ;
Peters, Ruth ;
Fletcher, Astrid E. ;
Staessen, Jan A. ;
Liu, Lisheng ;
Dumitrascu, Dan ;
Stoyanovsky, Vassil ;
Antikainen, Riitta L. ;
Nikitin, Yuri ;
Anderson, Craig ;
Belhani, Alli ;
Forette, Francoise ;
Rajkumar, Chakravarthi ;
Thijs, Lutgarde ;
Banya, Winston ;
Bulpitt, Christopher J. .
NEW ENGLAND JOURNAL OF MEDICINE, 2008, 358 (18) :1887-1898
[7]   Treatment of epilepsy in light of the most recent advances [J].
Beghi, Ettore ;
Giussani, Giorgia .
LANCET NEUROLOGY, 2019, 18 (01) :7-8
[8]   Aging and the Epidemiology of Epilepsy [J].
Beghi, Ettore ;
Giussani, Giorgia .
NEUROEPIDEMIOLOGY, 2018, 51 (3-4) :216-223
[9]  
Benjamin EJ, 2019, CIRCULATION, V139, pE56, DOI [10.1161/CIR.0000000000000746, 10.1161/CIR.0000000000000659]
[10]   The Pathobiology of TDP-43 C-Terminal Fragments in ALS and FTLD [J].
Berning, Britt A. ;
Walker, Adam K. .
FRONTIERS IN NEUROSCIENCE, 2019, 13