Inhibition of A2AR by AZD4635 induces anti-tumor immunity alone and in combination with anti-PD-L1 in preclinical models

被引：6

作者：

Borodovsky, Alexandra ^{[1
]}

Wang, Yanjun ^{[1
]}

Ye, Minwei ^{[1
]}

Shaw, Joseph C. ^{[1
]}

Sachsenmeier, Kris ^{[1
]}

Deng, Nanhua ^{[1
]}

Goodwin, Kelly ^{[1
]}

Clarke, James D. ^{[1
]}

Goodwin, Richard ^{[1
]}

Strittmatter, Nicole ^{[1
]}

Hay, Carl ^{[2
]}

Sah, Vasu ^{[1
]}

Deborah, Lawson ^{[1
]}

Reimer, Corinne ^{[1
]}

Congreve, Miles ^{[3
]}

Mason, Jonathan ^{[3
]}

Marshall, Fiona ^{[3
]}

Lyne, Paul ^{[1
]}

Woessner, Richard ^{[1
]}

机构：

[1] AstraZeneca, Boston, MA USA

[2] MedImmune, Gaithersburg, MD USA

[3] Heptares Therapeut, Welwyn Garden City, Herts, England

来源：

关键词：

D O I：

10.1158/1538-7445.AM2018-3751

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

3751

引用

页数：2