Distribution of Sorbitan Monooleate in poly(L-lactide-co-ε-caprolactone) nanofibers from emulsion electrospinning

被引:41
作者
Li, Xiaoqiang [2 ,3 ]
Su, Yan [2 ,3 ]
Zhou, Xu [3 ]
Mo, Xiumei [1 ,2 ,3 ]
机构
[1] Donghua Univ, Inst Biol Sci & Biotechnol, State Key Lab Modificat Chem Fibers & Polymer Mat, Shanghai 201620, Peoples R China
[2] Donghua Univ, Coll Mat Sci & Engn, Shanghai 201620, Peoples R China
[3] Donghua Univ, Coll Chem Chem Engn & Biotchnol, Biomat & Tissue Engn Lab, Shanghai 201620, Peoples R China
基金
美国国家科学基金会;
关键词
Nanofibers; Emulsion electrospinning; Distribution; PLLACL; Span80; FIBERS;
D O I
10.1016/j.colsurfb.2008.11.031
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
The aim of this study was to investigate the distribution of Sorbitan Monooleate (Span80) in poly(L-lactide-co-epsilon-caprolactone) (PLLACL) nanofibers from emulsion electrospinning. The hypothesis was that PLLACL/Span80 nanofibrous Mats Would have some Span80 on the surface of the composite nanofibers. To test the hypothesis, the electrospinning of emulsions made of PLLACL, chloroform, Span80, and distilled water to prepare PLLACL/Span80 nanofibers was systematically investigated. The morphology of PLLACL/Span80 nanofibers was investigated by atomic force microscopy. The surface hydrophilicity of the nanofibrous mats were examined by water contact angle test. The distribution of Span80 on the surface of nanofibrous mats was also confirmed by the performance of pig iliac endothelium cells on the nanofibrous mats. (C) 2008 Elsevier B.V. All rights reserved.
引用
收藏
页码:221 / 224
页数:4
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