High strength polymer/silicon nitride composites for dental restorations

被引:30
作者
Wang, Feng [1 ,2 ]
Guo, Jingshu [1 ]
Li, Ke [1 ]
Sun, Jian [3 ]
Zeng, Yuping [1 ]
Ning, Congqin [1 ]
机构
[1] Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China
[2] Norwegian Univ Sci & Technol NTNU, Dept Struct Engn, NTNU Nanomech Lab, N-7491 Trondheim, Norway
[3] Shanghai Jiao Tong Univ, Peoples Hosp 9, Sch Med, Dept Prosthodont, Shanghai 200011, Peoples R China
关键词
Porous Si3N4; Polymer-infiltrated Si3N4 composites; Dental restoration; Cytocompatibility; STRUCTURAL ORTHOPEDIC IMPLANTS; SILICON-NITRIDE; MECHANICAL-PROPERTIES; SI3N4; FABRICATION; RESIN; MICROSTRUCTURE;
D O I
10.1016/j.dental.2019.05.022
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Objectives. To fabricate polymer-infiltrated silicon nitride composite (PISNC) and evaluate the potential of PISNC in dental application. Methods. Porous silicon nitride (Si3N4) ceramics were fabricated through gelcasting and pressureless sintering. Polymer infiltrating was carried out then and composites were obtained after curing of polymer. Flexural strength and microstructures of porous ceramic scaffolds and polymer-infiltrated composites were obtained by three-point bending and SEM, respectively. Phase distributions of polymer-infiltrated ceramics were observed by EDS. Human gingival fibroblast cells (HGFs) were used to evaluate the cytocompatibility and IL-6 release. The cell morphology were observed by SEM. The amount of released IL-6 was investigated using ELISA test system. Results. Porosity and mechanical strength of porous ceramics ranged from 45.1 to 49.3% and 171.8-262.3 MPa, respectively. The bicontinuous structure of polymer-infiltrated composites possessed them with excellent mechanical properties. Porosity and mechanical strength of polymer-infiltrated Si3N4 composites ranged from 1.94 to 2.28% and 273-385.3 MPa, respectively. Additionally, the PISNC enhanced the initial adhesion and spreading activity of HGFs compared with PMMA. The PISNC showed similar IL-6 release performance with PMMA samples. Significances. The PISNC is a promising candidate for dental restorations and high-load medical applications. (C) 2019 The Academy of Dental Materials. Published by Elsevier Inc. All rights reserved.
引用
收藏
页码:1254 / 1263
页数:10
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