Fulminant Eosinophilic Myocarditis Associated With Visceral Larva Migrans Caused by Toxocara Canis Infection

被引:30
作者
Enko, Kenki [1 ]
Tada, Takeshi [1 ]
Ohgo, Keiko O. [1 ]
Nagase, Satoshi [1 ]
Nakamura, Kazufumi [1 ]
Ohta, Kei [2 ]
Ichiba, Shingo [2 ]
Ujike, Yoshihito [2 ]
Nawa, Yukifumi [3 ]
Maruyama, Haruhiko [3 ]
Ohe, Tohru [1 ]
Kusano, Kengo F. [1 ]
机构
[1] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Cardiovasc Med, Okayama 7008558, Japan
[2] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Emergency & Crit Care Med, Okayama 7008558, Japan
[3] Miyazaki Univ, Fac Med, Dept Parasitol, Miyazaki, Japan
关键词
Corticosteroids; Eosinophilia; Myocarditis; Toxocara canis; Visceral larva migrans; IMMUNOSUPPRESSIVE THERAPY;
D O I
10.1253/circj.CJ-08-0334
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 19-year-old man was transferred to hospital because of myocarditis with cardiogenic shock. Echocardiography showed a left ventricular ejection fraction of 23.8% and an intermediate amount of pericardial effusion. The patient immediately received an intra-aortic balloon pump and percutaneous cardiopulmonary support. Right ventricular endomyocardial biopsy was performed in the acute phase and showed extensive eosinophilic inflammatory cell infiltration, severe interstitial edema and moderate myocardial necrosis. High-dose corticosteroids were administered. Because the patient's antibody titer against Toxocara canis was high and his symptoms had appeared after eating raw deer meat, the diagnosis was fulminant eosinophilic myocarditis caused by a hypersensitivity reaction to visceral larval migrans. After starting high-dose corticosteroids, the ejection fraction dramatically, improved, the eosinophilia decreased and the patient made a full recovery. (Circ J 2009; 73: 1344-1348)
引用
收藏
页码:1344 / 1348
页数:5
相关论文
共 13 条
[1]   Myocarditis associated with visceral larva migrans due to Toxocara canis [J].
Abe, K ;
Shimokawa, H ;
Kubota, T ;
Nawa, Y ;
Takeshita, A .
INTERNAL MEDICINE, 2002, 41 (09) :706-708
[2]  
BEAVER PC, 1952, PEDIATRICS, V9, P7
[3]   EOSINOPHILIA AND ENDOMYOCARDIAL FIBROSIS [J].
BROCKING.IF ;
OLSEN, EGJ .
POSTGRADUATE MEDICAL JOURNAL, 1972, 48 (566) :740-741
[4]  
COOKSTON M, 1990, LAB INVEST, V62, pA22
[5]   Biventricular assist device placement and immunosuppression as therapy for necrotizing eosinophilic myocarditis [J].
Cooper, LT ;
Zehr, KJ .
NATURE CLINICAL PRACTICE CARDIOVASCULAR MEDICINE, 2005, 2 (10) :544-548
[6]  
DENT JH, 1956, AM J PATHOL, V32, P777
[7]  
*DRUGS JAP FOR, 2007, DRUGS JAP, P209
[8]   EFFECTS OF IMMUNOSUPPRESSIVE THERAPY IN BIOPSY-PROVED MYOCARDITIS AND BORDERLINE MYOCARDITIS ON LEFT-VENTRICULAR FUNCTION [J].
JONES, SR ;
HERSKOWITZ, A ;
HUTCHINS, GM ;
BAUGHMAN, KL .
AMERICAN JOURNAL OF CARDIOLOGY, 1991, 68 (04) :370-376
[9]   A CLINICAL-TRIAL OF IMMUNOSUPPRESSIVE THERAPY FOR MYOCARDITIS [J].
MASON, JW ;
OCONNELL, JB ;
HERSKOWITZ, A ;
ROSE, NR ;
MCMANUS, BM ;
BILLINGHAM, ME ;
MOON, TE ;
COSTANZO, MR ;
GRADY, K ;
KANTROWITZ, NE ;
ZELDIS, SM ;
KANE, S ;
COGLIANESE, ME ;
TOMEO, C ;
BACON, K ;
MCLAUGHLIN, PR ;
LIU, P ;
ROSS, B ;
PALACIOS, IF ;
DEC, W ;
BLOCK, B ;
COCCASPOFFARD, D ;
YOUNG, JB ;
LEON, C ;
CASTA, R ;
KINGRY, C ;
STRICKMAN, NE ;
HARLAN, M ;
FOWLER, N ;
ENGEL, P ;
NUNN, N ;
DAS, SK ;
SUHY, P ;
KLINE, E ;
GILLES, AJ ;
FRENCH, WJ ;
SKINNER, A ;
UNVERFERTH, DV ;
SARLING, R ;
NEWTON, P ;
WOODINGSCOTT, M ;
UNTEREKER, WJ ;
POLL, D ;
HOFFMAN, K ;
FRANK, J ;
FOWLES, R ;
MILLAR, K ;
FREEDMAN, L ;
LYVER, S ;
LATHAM, R .
NEW ENGLAND JOURNAL OF MEDICINE, 1995, 333 (05) :269-275
[10]   VISCERAL LARVA MIGRANS - A DISCUSSION BASED ON REVIEW OF LITERATURE [J].
MOK, CH .
CLINICAL PEDIATRICS, 1968, 7 (09) :565-+