One-Pot Synthesis of Pyrano[2,3-d]pyrimidinone Derivatives Catalyzed by L-Proline in Aqueous Media

被引：130

作者：

Bararjanian, M. ^{[1
]}

Balalaie, S. ^{[1
]}

Movassagh, B. ^{[1
]}

Amani, A. M. ^{[1
]}

机构：

[1] KN Toosi Univ Technol, Peptide Chem Res Grp, Tehran, Iran

来源：

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY | 2009年 / 6卷 / 02期

关键词：

Aqueous media; L-Proline; Pyrano[2,3-d]pyrimidinone; Domino Knoevenagel-cyclocondensation; ORGANIC-REACTIONS; PYRANO<2,3-D>PYRIMIDINE; FOCUS;

D O I：

10.1007/BF03245854

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient protocol has been developed for the synthesis of various pyrano[2,3-d]pyrimidinones from condensation of aromatic aldehydes, malononitrile and barbituric-or thiobarbituric acid in aqueous ethanol using L-proline as a neutral bifunctional catalyst.

引用

页码：436 / 442

页数：7

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