Use of whole-genome sequencing to guide a Clostridioides difficile diagnostic stewardship program

被引：7

作者：

Jakharia, Kunal K. ^{[1
]}

Ilaiwy, Ghassan ^{[1
]}

Moose, Siobhan S. ^{[2
,3
]}

Waga, Masashi ^{[4
]}

Appalla, Lakshmi ^{[5
]}

McAlduff, Joel D. ^{[6
]}

Karanfil, Lynne, V ^{[7
]}

McGann, Patrick T. ^{[5
]}

Wortmann, Glenn W. ^{[2
,3
,7
]}

机构：

[1] MedStar Washington Hosp Ctr, Dept Internal Med, Washington, DC USA

[2] MedStar Washington Hosp Ctr, Dept Infect Prevent, Washington, DC 20010 USA

[3] MedStar Washington Hosp Ctr, Dept Infect Dis, Washington, DC 20010 USA

[4] MedStar Washington Hosp Ctr, Dept Pathol & Lab Med, Washington, DC USA

[5] Walter Reed Army Inst Res, Multidrug Resistant Organism Repository & Surveil, Silver Spring, MD USA

[6] MedStar Hlth, Informat Serv, Columbia, MD USA

[7] MedStar Inst Qual & Safety, Infect Prevent, Columbia, MD 20008 USA

来源：

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY | 2019年 / 40卷 / 07期

关键词：

INFECTION;

D O I：

10.1017/ice.2019.124

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Whole-genome sequencing (WGS) has yielded new insights into the transmission patterns of healthcare facility-onset Clostridioides difficile infection (HO-CDI). WGS results prompted a focused diagnostic stewardship program, which was associated with a significant and sustained decrease in HO-CDI at large, urban hospital.

引用

页码：804 / 806

页数：3

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