Dynamics of forced biopolymer translocation

被引：58
作者：
Lehtola, V. V. [1 ]
Linna, R. P. [1 ]
Kaski, K. [1 ]
机构：
[1] Helsinki Univ Technol, Dept Biomed Engn & Computat Sci, FIN-02015 Helsinki, Finland
来源：
EPL | 2009年 / 85卷 / 05期
基金：
芬兰科学院;
关键词：
SOLID-STATE NANOPORE; POLYMER TRANSLOCATION; MEMBRANE; DNA; TRANSPORT; MOLECULES; MODEL; PORE;
D O I：
10.1209/0295-5075/85/58006
中图分类号：
O4 [物理学];
学科分类号：
0702 ;
摘要：
We present results from our simulations of biopolymer translocation in a solvent which explain the main experimental findings. The forced translocation can be described by simple force balance arguments for the relevant range of pore potentials in experiments and biological systems. Scaling of translocation time with polymer length varies with pore force and friction. Hydrodynamics affects this scaling and significantly reduces translocation times. Copyright (C) EPLA, 2009
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页数：6
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