Surface Plasmon Resonance Sensors: Methods of Surface Functionalization and Sensitivity Enhancement

被引:14
作者
Shynkarenko, O. V. [1 ]
Kravchenko, S. A. [1 ]
机构
[1] Natl Acad Sci Ukraine, VE Lashkaryov Inst Semicond Phys, UA-03028 Kiev, Ukraine
关键词
surface plasmon resonance (SPR); local surface plasmon resonance (LSPR); biosensors; functionalization; immobilization; gold nanoparticles; graphene; SELF-ASSEMBLED MONOLAYERS; ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY; COVALENT IMMOBILIZATION; PROTEIN IMMOBILIZATION; SILVER NANOPARTICLES; DNA HYBRIDIZATION; GRAPHENE OXIDE; NUCLEIC-ACIDS; GOLD; BIOSENSORS;
D O I
10.1007/s11237-015-9427-5
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Surface plasmon resonance (SPR) has proven to be an exceedingly powerful technique for real-time monitoring of biomolecular reactions. Methods for the immobilization of biomolecules on the surface of SPR sensors and graphene are surveyed. Approaches are offered for functionalization of the surface of nanoparticles used for the excitation of local SPR (LSPR). Examples are examined for the amplification of SPR by the combined use of metal nanoparticles and graphene. The feasibility of combining SPR and electrochemical methods was demonstrated.
引用
收藏
页码:273 / 292
页数:20
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