deep brain stimulation;
VIM;
essential tremor;
Parkinson disease;
D O I:
10.1590/S0004-282X2002000300017
中图分类号:
Q189 [神经科学];
学科分类号:
071006 ;
摘要:
Purpose: We present our results in 4 patients with tremor, in whom electrodes (uni and bilateral) for Deep Brain Stimulation (DBS) were implanted in the ventral intermediate nucleus (VIM) of the thalamus, Method: Four patients with disabling tremor, with drug-resistant spite of optimum therapeutic trials with poor response were referred to do surgery. Two patients had bilateral essential tremor. These patients were implanted with electrodes for DBS 3387 (Mectronic). Two patients had unilateral parkinsonian tremor and they received unilateral implantation of model 3387 DBS. Results: All four patients showed relieve of the tremor symptoms with significant tremor control seen at the scores. There were no definite adverse events after the electrodes implants for DBS; adverse events were transient and promptly reversed after the adjustment of the parameters. Conclusions: The results the authors found in this study indicate that VIM-stimulation is effective for tremor control either parkinsonian or essential tremor. The results correlate with the data in the literature.
机构:
Univ Toronto, Toronto Hosp, Western Div, Div Neurosurg, Toronto, ON M5T 2S8, CanadaUniv Toronto, Toronto Hosp, Western Div, Div Neurosurg, Toronto, ON M5T 2S8, Canada
机构:
Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Neurol, Boston, MA 02215 USAHarvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Neurol, Boston, MA 02215 USA
Shih, Ludy C.
LaFaver, Kathrin
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机构:
NINDS, Human Motor Control Sect, NIH, Bethesda, MD 20892 USAHarvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Neurol, Boston, MA 02215 USA
LaFaver, Kathrin
Lim, Chen
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机构:
New York Med Coll, Valhalla, NY 10595 USAHarvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Neurol, Boston, MA 02215 USA
Lim, Chen
Papavassiliou, Efstathios
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机构:
Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Div Neurosurg,Dept Surg, Boston, MA 02215 USAHarvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Neurol, Boston, MA 02215 USA
Papavassiliou, Efstathios
Tarsy, Daniel
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机构:
Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Neurol, Boston, MA 02215 USAHarvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Neurol, Boston, MA 02215 USA