The objective of this case report was to describe histopathological and immunohistochemical characteristics of the first reported basaloid carcinomas in the canine mammary gland. Two bitches were treated for tumors in the mammary gland and underwent mastectomy. Microscopic evaluation of these tumors revealed epithelial cells arranged in a predominantly solid pattern with hyperchromatic peripheral cells arranged in a palisade pattern. Metastases in regional lymph nodes were found in both animals, and one bitch exhibited pulmonary metastasis. Immunohistochemistry revealed positive labeling for the basal cell markers cytokeratin 14 and p63. Histopathological and immunohistochemical findings led to diagnoses of basaloid carcinoma of the canine mammary gland with regional and distant metastasis.
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Vardhman Mahavir Med Coll & Safdarjung Hosp, Dept Otorhinolaryngol & Head & Neck Surg, New Delhi, IndiaVardhman Mahavir Med Coll & Safdarjung Hosp, Dept Otorhinolaryngol & Head & Neck Surg, New Delhi, India
Chaudhary, Neena
Trehan, Sandeep
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Vardhman Mahavir Med Coll & Safdarjung Hosp, Dept Otorhinolaryngol & Head & Neck Surg, New Delhi, IndiaVardhman Mahavir Med Coll & Safdarjung Hosp, Dept Otorhinolaryngol & Head & Neck Surg, New Delhi, India
Trehan, Sandeep
Janardhan, Meghana
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Vardhman Mahavir Med Coll & Safdarjung Hosp, Dept Pathol, New Delhi, IndiaVardhman Mahavir Med Coll & Safdarjung Hosp, Dept Otorhinolaryngol & Head & Neck Surg, New Delhi, India
Janardhan, Meghana
Khanna, Geetika
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Vardhman Mahavir Med Coll & Safdarjung Hosp, Dept Otorhinolaryngol & Head & Neck Surg, New Delhi, IndiaVardhman Mahavir Med Coll & Safdarjung Hosp, Dept Otorhinolaryngol & Head & Neck Surg, New Delhi, India
机构:
Cornell Univ, Coll Vet Med, Baker Inst Anim Hlth, Ithaca, NY 14853 USACornell Univ, Coll Vet Med, Baker Inst Anim Hlth, Ithaca, NY 14853 USA
Bussche, L.
Harms, C.
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Southern Equine Serv, Aiken, SC USA
Rood & Riddle Equine Hosp Saratoga, New York, NY USACornell Univ, Coll Vet Med, Baker Inst Anim Hlth, Ithaca, NY 14853 USA
Harms, C.
Buckles, E. L.
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Cornell Univ, Coll Vet Med, Anat Pathol, Ithaca, NY 14853 USACornell Univ, Coll Vet Med, Baker Inst Anim Hlth, Ithaca, NY 14853 USA
Buckles, E. L.
Whelchel, D.
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Southern Equine Serv, Aiken, SC USA
Univ Missouri, Dept Vet Med & Surg, Columbia, MO 65211 USACornell Univ, Coll Vet Med, Baker Inst Anim Hlth, Ithaca, NY 14853 USA
Whelchel, D.
Brosnahan, M.
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Cornell Univ, Coll Vet Med, Baker Inst Anim Hlth, Ithaca, NY 14853 USACornell Univ, Coll Vet Med, Baker Inst Anim Hlth, Ithaca, NY 14853 USA
Brosnahan, M.
Van de Walle, G. R.
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Cornell Univ, Coll Vet Med, Baker Inst Anim Hlth, Ithaca, NY 14853 USACornell Univ, Coll Vet Med, Baker Inst Anim Hlth, Ithaca, NY 14853 USA