The role of the microbiome in kidney stone formation

被引：71

作者：

Mehta, Mansi ^{[1
]}

Goldfarb, David S. ^{[1
,2
]}

Nazzal, Lama ^{[1
]}

机构：

[1] NYU, Sch Med, Div Nephrol, New York, NY USA

[2] New York Harbor VA Healthcare Syst, New York, NY USA

来源：

INTERNATIONAL JOURNAL OF SURGERY | 2016年 / 36卷

关键词：

Microbiota; Nephrolithiasis; Urolithiasis; BACTERIUM OXALOBACTER-FORMIGENES; URINARY OXALATE EXCRETION; DEGRADING BACTERIA; COLONIZATION; GUT; PROBIOTICS; MODEL;

D O I：

10.1016/j.ijsu.2016.11.024

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Nephrolithiasis is a complex disease of worldwide prevalence that is influenced by both genetic and environmental factors. About 75% of kidney stones are predominantly composed of calcium oxalate and urinary oxalate is considered a crucial risk factor. Microorganisms may have a role in the pathogenesis and prevention of kidney stones and the involvement of the intestinal microbiome in this renal disease has been a recent area of interest. Oxalobacter formigenes is a gram negative bacteria that degrades oxalate in the gut decreasing urinary oxalate excretion. In this review, we examine the data studying the role of Oxalobacter formigenes in kidney stone disease in humans and animals, the effect of antibiotics on its colonization, and the potential role of probiotics and whole microbial communities as therapeutic interventions. (C) 2016 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved.

引用

页码：607 / 612

页数：6

共 32 条

[1] Oxalate-Degrading Bacteria of the Human Gut as Probiotics in the Management of Kidney Stone Disease
Abratt, Valerie R.
Reid, Sharon J.
[J]. ADVANCES IN APPLIED MICROBIOLOGY, VOL 72, 2010, 72 : 63 - 87
[2] OXALOBACTER-FORMIGENES GEN-NOV, SP-NOV - OXALATE-DEGRADING ANAEROBES THAT INHABIT THE GASTROINTESTINAL-TRACT
ALLISON, MJ
DAWSON, KA
MAYBERRY, WR
FOSS, JG
[J]. ARCHIVES OF MICROBIOLOGY, 1985, 141 (01) : 1 - 7
[3] OXALATE DEGRADATION BY GASTROINTESTINAL BACTERIA FROM HUMANS
ALLISON, MJ
COOK, HM
MILNE, DB
GALLAGHER, S
CLAYMAN, RV
[J]. JOURNAL OF NUTRITION, 1986, 116 (03) : 455 - 460
[4] ANANTHARAM V, 1989, J BIOL CHEM, V264, P7244
[5] Arvans D., 2016, J AM SOC NEPHROL
[6] The Presence of Oxalobacter formigenes in the Microbiome of Healthy Young Adults
Barnett, Clea
Nazzal, Lama
Goldfarb, David S.
Blaser, Martin J.
[J]. JOURNAL OF UROLOGY, 2016, 195 (02) : 499 - 506
[7] ESSAY What are the consequences of the disappearing human microbiota?
Blaser, Martin J.
Falkow, Stanley
[J]. NATURE REVIEWS MICROBIOLOGY, 2009, 7 (12) : 887 - 894
[8] The construction of an oxalate-degrading intestinal stem cell population in mice: a potential new treatment option for patients with calcium oxalate calculus
Chen, Zhiqiang
Liu, Guanlin
Ye, Zhangqun
Kong, Debo
Yao, Lingfang
Guo, Hui
Yang, Weimin
Yu, Xiao
[J]. UROLOGICAL RESEARCH, 2012, 40 (02): : 131 - 141
[9] Oxalobacter formigenes and its potential role in human health
Duncan, SH
Richardson, AJ
Kaul, P
Holmes, RP
Allison, MJ
Stewart, CS
[J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2002, 68 (08) : 3841 - 3847
[10] Ellis Melissa E, 2016, J Proteomics Bioinform, V9, P19

← 1 2 3 4 →