Electrochemistry/mass spectrometry (EG/MS) - A new tool to study drug metabolism and reaction mechanisms

被引：93

作者：

Karst, U ^{[1
]}

机构：

[1] Univ Twente, Dept Chem Anal & MESA, Inst Nanotechnol, NL-7500 AE Enschede, Netherlands

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 19期

关键词：

derivatization; electrochemistry; liquid chromatography; mass spectrometry; metabolism;

D O I：

10.1002/anie.200301763

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：2476 / 2478

页数：3

共 16 条

[1] Fast liquid chromatography-electrochemistry-mass spectrometry of ferrocenecarboxylic acid esters [J].

Diehl, G ;

Karst, U .

JOURNAL OF CHROMATOGRAPHY A, 2002, 974 (1-2) :103-109

[2] Liquid chromatography with post-column electrochemical treatment and mass spectrometric detection of non-polar compounds [J].

Diehl, G ;

Liesener, A ;

Karst, U .

ANALYST, 2001, 126 (03) :288-290

[3] On-line electrochemistry - MS and related techniques [J].

Diehl, G ;

Karst, U .

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2002, 373 (06) :390-398

[4]

Gun J, 2003, EUR J INORG CHEM, P482

[5] Reduction of [(C5Me5)2Mo2O5] and [(C5Me5)2Mo2O4] in methanol/water/trifluoroacetate solutions investigated by combined on-line electrochemistry/electrospray-ionization mass spectrometry [J].

Gun, J ;

Modestov, A ;

Lev, O ;

Poli, R .

EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2003, (12) :2264-2272

[6] ELECTROCHEMICAL THERMOSPRAY MASS-SPECTROMETRY [J].

HAMBITZER, G ;

HEITBAUM, J .

ANALYTICAL CHEMISTRY, 1986, 58 (06) :1067-1070

[7] Strategies for the liquid chromatographic-mass spectrometric analysis of non-polar compounds [J].

Hayen, H ;

Karst, U .

JOURNAL OF CHROMATOGRAPHY A, 2003, 1000 (1-2) :549-565

[8] Chemical and on-line electrochemical reduction of metalloproteins with high-resolution electrospray ionization mass spectrometry detection [J].

Johnson, KA ;

Shira, BA ;

Anderson, JL ;

Amster, IJ .

ANALYTICAL CHEMISTRY, 2001, 73 (04) :803-808

[9]

Jurva U, 2000, RAPID COMMUN MASS SP, V14, P529, DOI 10.1002/(SICI)1097-0231(20000331)14:6<529::AID-RCM904>3.0.CO

[10]

2-H

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