Aberrant resting-state functional connectivity in a genetic rat model of depression

被引：16

作者：

Williams, Kathleen A. ^{[1
]}

Mehta, Neha S. ^{[2
,3
]}

Redei, Eva E. ^{[2
,3
]}

Wang, Lei ^{[1
,2
]}

Procissi, Daniel ^{[1
]}

机构：

[1] Northwestern Univ, Dept Radiol, Feinberg Sch Med, Chicago, IL 60611 USA

[2] Northwestern Univ, Dept Psychiat & Behav Sci, Feinberg Sch Med, Chicago, IL 60611 USA

[3] Northwestern Univ, Norman & Helen Asher Ctr Study Depress Disorders, Feinberg Sch Med, Chicago, IL 60611 USA

来源：

PSYCHIATRY RESEARCH-NEUROIMAGING | 2014年 / 222卷 / 1-2期

关键词：

Hippocampus; Wistar Kyoto More Immobile; Functional MRI; NETWORKS;

D O I：

10.1016/j.pscychresns.2014.02.001

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Abnormal intrinsic functional connectivity, measured by resting-state functional MRI, has been reported in major depressive disorder (MDD). Our study is the first to demonstrate hypo- and hyperconnectivity between the hippocampus and cortical, subcortical regions in a genetic animal model of depression, similar to connectivity anomalies found in MDD. (C) 2014 Elsevier Ireland Ltd. All rights reserved,

引用

页码：111 / 113

页数：3

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