Aberrant resting-state functional connectivity in a genetic rat model of depression

被引：16
|
作者：
Williams, Kathleen A. [1 ]
Mehta, Neha S. [2 ,3 ]
Redei, Eva E. [2 ,3 ]
Wang, Lei [1 ,2 ]
Procissi, Daniel [1 ]
机构：
[1] Northwestern Univ, Dept Radiol, Feinberg Sch Med, Chicago, IL 60611 USA
[2] Northwestern Univ, Dept Psychiat & Behav Sci, Feinberg Sch Med, Chicago, IL 60611 USA
[3] Northwestern Univ, Norman & Helen Asher Ctr Study Depress Disorders, Feinberg Sch Med, Chicago, IL 60611 USA
来源：
PSYCHIATRY RESEARCH-NEUROIMAGING | 2014年 / 222卷 / 1-2期
关键词：
Hippocampus; Wistar Kyoto More Immobile; Functional MRI; NETWORKS;
D O I：
10.1016/j.pscychresns.2014.02.001
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Abnormal intrinsic functional connectivity, measured by resting-state functional MRI, has been reported in major depressive disorder (MDD). Our study is the first to demonstrate hypo- and hyperconnectivity between the hippocampus and cortical, subcortical regions in a genetic animal model of depression, similar to connectivity anomalies found in MDD. (C) 2014 Elsevier Ireland Ltd. All rights reserved,
引用
收藏
页码：111 / 113
页数：3
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