Organ at risk delineation for radiation therapy clinical trials: Global Harmonization Group consensus guidelines

被引:68
作者
Mir, Romaana [1 ]
Kelly, Sarah M. [2 ,3 ]
Xiao, Ying [4 ]
Moore, Alisha [5 ]
Clark, Catharine H. [6 ,7 ]
Clementel, Enrico [2 ]
Corning, Coreen [2 ]
Ebert, Martin [5 ,8 ,9 ,10 ]
Hoskin, Peter [1 ]
Hurkmans, Coen W. [11 ]
Ishikura, Satoshi [12 ,13 ]
Kristensen, Ingrid [14 ]
Kry, Stephen F. [15 ]
Lehmann, Joerg [5 ,16 ,17 ]
Michalski, Jeff M. [18 ]
Monti, Angelo F. [2 ,19 ]
Nakamura, Mitsuhiro [12 ,20 ]
Thompson, Kenton [5 ,21 ]
Yang, Huiqi [22 ]
Zubizarreta, Eduardo [23 ]
Andratschke, Nicolaus [2 ,24 ]
Miles, Elizabeth [1 ]
机构
[1] Mt Vernon Canc Ctr, Natl Radiotherapy Trials Qual Assurance RTTQA Grp, Northwood, Middx, England
[2] European Org Res & Treatment Canc EORTC Headquart, Brussels, Belgium
[3] SIOP Europe, Qual & Excellence Radiotherapy & Imaging Children, Brussels, Belgium
[4] Univ Penn, Imaging & Radiat Oncol Core IROC, Philadelphia, PA 19104 USA
[5] Trans Tasman Radiat Oncol Grp TROG, Newcastle, NSW, Australia
[6] Royal Surrey NHS Fdn Trust, Natl Radiotherapy Trials Qual Assurance RTTQA Grp, Guildford, Surrey, England
[7] Natl Phys Lab NPL, Teddington, Middx, England
[8] Sir Charles Gairdner Hosp, Nedlands, WA, Australia
[9] Univ Western Australia, Nedlands, WA, Australia
[10] Univ Western Australia, Sch Phys Math & Comp, Nedlands, WA, Australia
[11] Catharina Hosp, Dept Radiat Oncol, Eindhoven, Netherlands
[12] Japan Clin Oncol Grp JCOG, Nagoya, Aichi, Japan
[13] Nagoya City Univ, Grad Sch Med Sci, Dept Radiol, Nagoya, Aichi, Japan
[14] Skane Univ Hosp, Radiat Phys, Dept Hematol Oncol & Radiat Phys, Malmo, Sweden
[15] Univ Texas MD Anderson Canc Ctr, Imaging & Radiat Oncol Core IROC, Houston, TX 77030 USA
[16] Calvary Mater Hosp, Dept Radiat Oncol, Waratah, NSW, Australia
[17] Univ Newcastle, Sch Math & Phys Sci, Callaghan, NSW, Australia
[18] Washington Univ, Sch Med, Dept Radiat Oncol, St Louis, MO USA
[19] ASST Niguarda Hosp, Dept Med Phys, Milan, Italy
[20] Kyoto Univ, Grad Sch Med, Div Med Phys, Dept Informat Technol & Med Engn,Human Hlth Sci, Kyoto, Japan
[21] Peter MacCallum Canc Ctr, Melbourne, Vic, Australia
[22] Cambridge Univ Hosp NHS Fdn Trust, Cambridge, England
[23] Int Atom Energy Agcy IAEA, Div Human Hlth, Appl Radiat Biol & Radiotherapy Sect, Vienna, Austria
[24] Univ Zurich, Univ Zurich Hosp, Dept Radiat Oncol, Zurich, Switzerland
关键词
Radiotherapy; Contouring; Delineation; Nomenclature; Standardization; Quality assurance;
D O I
10.1016/j.radonc.2020.05.038
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background and purpose: The Global Quality Assurance of Radiation Therapy Clinical Trials Harmonization Group (GHG) is a collaborative group of Radiation Therapy Quality Assurance (RTQA) Groups harmonizing and improving RTQA for multi-institutional clinical trials. The objective of the GHG OAR Working Group was to unify OAR contouring guidance across RTQA groups by compiling a single reference list of OARs in line with AAPM TG 263 and ASTRO, together with peer-reviewed, anatomically defined contouring guidance for integration into clinical trial protocols independent of the radiation therapy delivery technique. Materials and methods: The GHG OAR Working Group comprised of 22 multi-professional members from 6 international RTQA Groups and affiliated organizations conducted the work in 3 stages: (1) Clinical trial documentation review and identification of structures of interest (2) Review of existing contouring guidance and survey of proposed OAR contouring guidance (3) Review of survey feedback with recommendations for contouring guidance with standardized OAR nomenclature. Results: 157 clinical trials were examined; 222 OAR structures were identified. Duplicates, nonanatomical, non-specific, structures with more specific alternative nomenclature, and structures identified by one RTQA group were excluded leaving 58 structures of interest. 6 OAR descriptions were accepted with no amendments, 41 required minor amendments, 6 major amendments, 20 developed as a result of feedback, and 5 structures excluded in response to feedback. The final GHG consensus guidance includes 73 OARs with peer-reviewed descriptions (Appendix A). Conclusion: We provide OAR descriptions with standardized nomenclature for use in clinical trials. A more uniform dataset supports the delivery of clinically relevant and valid conclusions from clinical trials. (C) 2020 The Authors. Published by Elsevier B.V. Radiotherapy and Oncology 150 (2020) 30-39 This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
引用
收藏
页码:30 / 39
页数:10
相关论文
共 46 条
[1]  
American Society for Radiation Oncology (ASTRO), 2017 RO ILS YEAR REV
[2]  
[Anonymous], 2010, J INT COMMISSION RAD
[3]  
[Anonymous], ASTRONEWS
[4]  
[Anonymous], 2019, 5 PUBL HLTH ENGL
[5]  
[Anonymous], 2009, Pennsylvania Patient Safety Advisory, V6, P87
[6]  
[Anonymous], 2008, TRANS 2 D RAD 3 D CO
[7]   Adequate margins for random setup uncertainties in head-and-neck IMRT [J].
Astreinidou, E ;
Bel, A ;
Raaijmakers, CPJ ;
Terhaard, CHJ ;
Lagendijk, JJW .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2005, 61 (03) :938-944
[8]   Interobserver delineation uncertainty in involved-node radiation therapy (INRT) for early-stage Hodgkin lymphoma: on behalf of the Radiotherapy Committee of the EORTC lymphoma group [J].
Aznar, Marianne C. ;
Girinsky, Theodore ;
Berthelsen, Anne Kiil ;
Aleman, Berthe ;
Beijert, Max ;
Hutchings, Martin ;
Lievens, Yolande ;
Meijnders, Paul ;
Petersen, Peter Meidahl ;
Schut, Deborah ;
Maraldo, Maja V. ;
van der Maazen, Richard ;
Specht, Lena .
ACTA ONCOLOGICA, 2017, 56 (04) :608-613
[9]   Agreement Among RTOG Sarcoma Radiation Oncologists in Contouring Suspicious Peritumoral Edema for Preoperative Radiation Therapy of Soft Tissue Sarcoma of the Extremity [J].
Bahig, Houda ;
Roberge, David ;
Bosch, Walter ;
Levin, William ;
Petersen, Ivy ;
Haddock, Michael ;
Freeman, Carolyn ;
DeLaney, Thomas F. ;
Abrams, Ross A. ;
Indelicato, Danny J. ;
Baldini, Elizabeth H. ;
Hitchcock, Ying ;
Kirsch, David G. ;
Kozak, Kevin R. ;
Wolfson, Aaron ;
Wang, Dian .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2013, 86 (02) :298-303
[10]   Retroperitoneal Sarcoma Target Volume and Organ at Risk Contour Delineation Agreement Among NRG Sarcoma Radiation Oncologists [J].
Baldini, Elizabeth H. ;
Abrams, Ross A. ;
Bosch, Walter ;
Roberge, David ;
Haas, Rick L. M. ;
Catton, Charles N. ;
Indelicato, Daniel J. ;
Olsen, Jeffrey R. ;
Deville, Curtiland ;
Chen, Yen-Lin ;
Finkelstein, Steven E. ;
DeLaney, Thomas F. ;
Wang, Dian .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2015, 92 (05) :1053-1059