Synthesis and resolution of 2-amino-5-aza[6]helicene

被引：3

作者：

Bhalodi, Esha H. ^{[1
]}

Patel, Krupa N. ^{[1
]}

Bedekar, Ashutosh, V ^{[1
]}

机构：

[1] Maharaja Sayajirao Univ Baroda, Fac Sci, Dept Chem, Vadodara 390002, India

来源：

TETRAHEDRON | 2022年 / 114卷

关键词：

Aza[6]helicene; CD analysis; Helical isomers; Single crystal analysis; ONE HUNDRED YEARS; STEREOSELECTIVE SYNTHESES; CHIRAL RECOGNITION; CRYSTAL-STRUCTURES; SMALL MOLECULES; PART; CARBAZOLE; HELICENE; DERIVATIVES; PHOTOCYCLIZATION;

D O I：

10.1016/j.tet.2022.132761

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of 2-amino-5-aza[6]helicene and its derivatives is reported. The diastereomeric (R)menthylcarbamate derivative of this aza[6]helicene is prepared and its isomers were physically separated by column chromatography and their optical properties were measured. Optically pure isomer (P)2-amino-5-aza[6]helicene was generated and its Boc-derivative was prepared.(c) 2022 Elsevier Ltd. All rights reserved.

引用

页数：7

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