Death, destruction, danger and dendritic cells

被引:20
作者
Austyn, JM [1 ]
机构
[1] Royal Prince Alfred Hosp, Camperdown, NSW 2050, Australia
关键词
D O I
10.1038/15182
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Dendritic cells are known to be involved in recognition of foreign antigens and initiation of specific T-cell responses. The 'danger hypothesis' suggests that the immune system can also respond to endogenous signals of distress. New data indicate that dendritic cells are the first to respond to these signals, although the mechanisms involved in their activation are unclear (pages 1249–1255).
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收藏
页码:1232 / 1233
页数:2
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