PET/CT Staging and Response Evaluation of Post-Transplantation Lymphoproliferative Disease (PTLD)

被引：10

作者：

Chowdhury, Fahmid U. ^{[1
]}

Sheerin, Fintan ^{[2
]}

Bradley, Kevin M. ^{[2
,3
]}

Gleeson, Fergus V. ^{[2
,3
]}

机构：

[1] St James Univ Hosp, Dept Radiol & Nucl Med, Leeds, W Yorkshire, England

[2] Oxford Radcliffe Hosp, Dept Radiol, Oxford, England

[3] Oxford Radcliffe Hosp, Dept Nucl Med, Oxford, England

来源：

CLINICAL NUCLEAR MEDICINE | 2009年 / 34卷 / 06期

关键词：

post-transplantation lymphoproliferative disease; PTLD; FDG; PET/CT; FDG-PET; MANAGEMENT;

D O I：

10.1097/RLU.0b013e3181a3456a

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A 40-year-old man presented with nonspecific chest pain 14 months following a cadaveric renal transplant for diabetic nephropathy. He was on immunosuppressive therapy with tacrolimus. Computed tomography (CT) of the chest demonstrated a destructive rib lesion with a large soft tissue component. Core biopsy confirmed a diagnosis of monomorphic post-transplantation lymphoproliferative disease strongly positive for Epstein-Barr virus. Staging fluorodeoxyglucose positron emission tomography (PET)/CT detected hypermetabolic osseous lesions, involvement of several nodal groups, and focal uptake within the liver. After reduction of immunosuppression, a follow-up PET/CT scan showed complete metabolic remission. This case highlights the utility of fluorodeoxyglucose PET/CT in the staging and response evaluation of post-transplantation lymphoproliferative disease.

引用

页码：386 / 387

页数：2

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