Efficacy comparison between mometasone furoate combined with azelastine hydrochloride and azelastine hydrochloride alone in treatment of allergic rhinitis with adenoidal hypertrophy in children

Objective: This study aimed to compare efficacy between mometasone furoate combined with azelastine hydrochloride and azelastine hydrochloride alone in the treatment of allergic rhinitis (AR) with adenoidal hypertrophy (AH) in children. Methods: One hundred and fifty-seven children with AR and AH were retrospectively analyzed. Children treated with azelastine hydrochloride nasal spray and mometasone furoate nasal spray were included in group A, while children treated with azelastine hydrochloride nasal spray alone in group B. The two groups of children were compared in terms of total nasal symptom score, vital signs score, Mini Rhinoconjunctivitis Quality of Life Questionnaire (MiniRQLQ) score and clinical efficacy. Results: In groups A and B, the total nasal symptom, vital signs and MiniRQLQ scores at 2 weeks after treatment were lower than those before treatment (all P < 0.05). The three scores in group A were better than those in group B (all P < 0.05). Conclusion: In conclusion, mometasone furoate combined with azelastine hydrochloride was more effective than mometasone furoate nasal spray alone in the treatment of children with AR and AH, worthy of clinical promotion.