The Evaluation and Management of Adult Intracerebral Hemorrhage

被引:13
作者
Cai, Xuemei [1 ]
Rosand, Jonathan [2 ]
机构
[1] Massachusetts Gen Hosp, Div Neurocrit Care & Emergency Neurol, Boston, MA 02114 USA
[2] Massachusetts Gen Hosp, Ctr Human Genet Res, Div Neurocrit Care & Emergency Neurol, Boston, MA 02114 USA
关键词
intracerebral hemorrhage; diagnosis; treatment; coagulopathy; surgery; INITIAL CONSERVATIVE TREATMENT; EXTERNAL VENTRICULAR DRAINAGE; PREDICTING HEMATOMA EXPANSION; MINIMALLY INVASIVE SURGERY; HEALTH-CARE PROFESSIONALS; CEREBELLAR HEMORRHAGE; INTRAVENTRICULAR HEMORRHAGE; BLOOD-PRESSURE; VENOUS THROMBOEMBOLISM; ENDOSCOPIC SURGERY;
D O I
10.1055/s-0035-1564687
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Intracerebral hemorrhage (ICH) is the most disabling and deadly form of stroke. Although mortality remains high, new data suggest that outcomes can be improved with standardized medical care. In this review, the authors outline the most up-to-date knowledge, including the results of the latest phase III clinical trials on the specialized care needed to treat patients with ICH. They provide an overview on how to achieve rapid diagnosis and the initial steps of intervention to reduce hematoma volume or prevent expansion by modifying potentially treatable conditions, such as underlying vascular etiologies, blood pressure control, and coagulopathies. Grading scales can help identify patients at risk for hematoma expansion and functional disabilities and guide clinical decision making. Other medical management topics important to recovery and prevention of secondary brain injury include seizure prevention and treatment, glycemic control, temperature control, and deep venous thrombosis prophylaxis and treatment. Treatment options in surgery are also possible in select patients; there are emerging studies regarding minimally invasive surgery for the management of ICH. These aggressive therapies are essential to lower themorbidity andmortality of patients presenting with ICH.
引用
收藏
页码:638 / 645
页数:8
相关论文
共 83 条
[1]   The Spot Sign Score in Primary Intracerebral Hemorrhage Identifies Patients at Highest Risk of In-Hospital Mortality and Poor Outcome Among Survivors [J].
Almandoz, Josser E. Delgado ;
Yoo, Albert J. ;
Stone, Michael J. ;
Schaefer, Pamela W. ;
Oleinik, Alexandra ;
Brouwers, H. Bart ;
Goldstein, Joshua N. ;
Rosand, Jonathan ;
Lev, Michael H. ;
Gonzalez, R. Gilberto ;
Romero, Javier M. .
STROKE, 2010, 41 (01) :54-60
[2]   Rapid Blood-Pressure Lowering in Patients with Acute Intracerebral Hemorrhage [J].
Anderson, Craig S. ;
Heeley, Emma ;
Huang, Yining ;
Wang, Jiguang ;
Stapf, Christian ;
Delcourt, Candice ;
Lindley, Richard ;
Robinson, Thompson ;
Lavados, Pablo ;
Neal, Bruce ;
Hata, Jun ;
Arima, Hisatomi ;
Parsons, Mark ;
Li, Yuechun ;
Wang, Jinchao ;
Heritier, Stephane ;
Li, Qiang ;
Woodward, Mark ;
Simes, R. John ;
Davis, Stephen M. ;
Chalmers, John .
NEW ENGLAND JOURNAL OF MEDICINE, 2013, 368 (25) :2355-2365
[3]  
[Anonymous], 2009, ADULT INTRACEREBRAL
[4]   External ventricular drainage alone versus endoscopic surgery for severe intraventricular hemorrhage: a comparative retrospective analysis on outcome and shunt dependency [J].
Basaldella, Luca ;
Marton, Elisabetta ;
Fiorindi, Alessandro ;
Scarpa, Bruno ;
Badreddine, Hadi ;
Longatti, Pierluigi .
NEUROSURGICAL FOCUS, 2012, 32 (04)
[5]   Withdrawal of support in intracerebral hemorrhage may lead to self-fulfilling prophecies [J].
Becker, KJ ;
Baxter, AB ;
Cohen, WA ;
Bybee, HM ;
Tirschwell, DL ;
Newell, DW ;
Winn, HR ;
Longstreth, WT .
NEUROLOGY, 2001, 56 (06) :766-772
[6]   ULTRA-EARLY EVALUATION OF INTRACEREBRAL HEMORRHAGE [J].
BRODERICK, JP ;
BROTT, TG ;
TOMSICK, T ;
BARSAN, W ;
SPILKER, J .
JOURNAL OF NEUROSURGERY, 1990, 72 (02) :195-199
[7]   Prophylactic, Endovascularly Based, Long-Term Normothermia in ICU Patients With Severe Cerebrovascular Disease Bicenter Prospective, Randomized Trial [J].
Broessner, Gregor ;
Beer, Ronny ;
Lackner, Peter ;
Helbok, Raimund ;
Fischer, Marlene ;
Pfausler, Bettina ;
Rhorer, Janelle ;
Kueppers-Tiedt, Lea ;
Schneider, Dietmar ;
Schmutzhard, Erich .
STROKE, 2009, 40 (12) :E657-E665
[8]   HYPERTENSION AS A RISK FACTOR FOR SPONTANEOUS INTRACEREBRAL HEMORRHAGE [J].
BROTT, T ;
THALINGER, K ;
HERTZBERG, V .
STROKE, 1986, 17 (06) :1078-1083
[9]   Predicting Hematoma Expansion After Primary Intracerebral Hemorrhage [J].
Brouwers, H. Bart ;
Chang, Yuchiao ;
Falcone, Guido J. ;
Cai, Xuemei ;
Ayres, Alison M. ;
Battey, Thomas W. K. ;
Vashkevich, Anastasia ;
McNamara, Kristen A. ;
Valant, Valerie ;
Schwab, Kristin ;
Orzell, Susannah C. ;
Bresette, Linda M. ;
Feske, Steven K. ;
Rost, Natalia S. ;
Romero, Javier M. ;
Viswanathan, Anand ;
Chou, Sherry H. -Y. ;
Greenberg, Steven M. ;
Rosand, Jonathan ;
Goldstein, Joshua N. .
JAMA NEUROLOGY, 2014, 71 (02) :158-164
[10]   Pearls and Oy-sters: Small but consequential Intracerebral hemorrhage caused by lenticulostriate artery aneurysm [J].
Cai, Xuemei ;
Han, Steve ;
Feske, Steven K. ;
Chou, Sherry H. -Y. .
NEUROLOGY, 2013, 80 (09) :E89-E91