Mechanisms of focal ventricular tachycardia in humans

被引:8
作者
Markowitz, Steven M. [1 ]
Lerman, Bruce B. [1 ]
机构
[1] Weill Cornell Med Coll, Div Cardiol, Dept Med, New York, NY 10021 USA
关键词
Ventricular tachycardia; Triggered activity; Automaticity; MYOCARDIAL-INFARCTION; OUTFLOW TRACT; TRIGGERED ACTIVITY; DELAYED AFTERDEPOLARIZATIONS; CATHETER ABLATION; LOCALIZED REENTRY; PURKINJE-FIBERS; ORIGIN; CELLS; AUTOMATICITY;
D O I
10.1016/j.hrthm.2009.02.034
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In classifying ventricular arrhythmias, a fundamental distinction is made between focal and macroreentrant mechanisms. Focal arrhythmias demonstrate early activation at a particular site with centrifugal spread of the impulse from this site of origin. In contrast, macroreentrant rhythms involve contiguous but spatially distributed areas of activation. Despite advances in muttielectrode and electroanatomical mapping, the distinction of a focal from a macroreentrant mechanism is sometimes problematic.
引用
收藏
页码:S81 / S85
页数:5
相关论文
共 32 条
[1]   Ionic, molecular, and cellular bases of QT-interval prolongation and torsade de pointes [J].
Antzelevitch, Charles .
EUROPACE, 2007, 9 :4-15
[2]   Successful catheter ablation of electrical storm after myocardial infarction [J].
Bänsch, D ;
Oyang, F ;
Antz, M ;
Arentz, T ;
Weber, R ;
Val-Mejias, JE ;
Ernst, S ;
Kuck, KH .
CIRCULATION, 2003, 108 (24) :3011-3016
[3]   Ca2+ transients and Ca2+ waves in Purkinje cells -: Role in action potential initiation [J].
Boyden, PA ;
Pu, JL ;
Pinto, J ;
ter Keurs, HEDJ .
CIRCULATION RESEARCH, 2000, 86 (04) :448-455
[4]   Arrhythmogenic mechanisms in a mouse model of catecholaminergic polymorphic ventricular tachycardia [J].
Cerrone, Marina ;
Noujaim, Sami F. ;
Tolkacheva, Elena G. ;
Talkachou, Arkadzi ;
O'Connell, Ryan ;
Berenfeld, Omer ;
Anumonwo, Justus ;
Pandit, Sandeep V. ;
Vikstrom, Karen ;
Napolitano, Carlo ;
Priori, Silvia G. ;
Jalife, Jose .
CIRCULATION RESEARCH, 2007, 101 (10) :1039-1048
[5]   THE EFFECTS OF SINGLE PREMATURE STIMULI ON AUTOMATIC AND TRIGGERED RHYTHMS IN ISOLATED CANINE PURKINJE-FIBERS [J].
DANGMAN, KH ;
HOFFMAN, BF .
CIRCULATION, 1985, 71 (04) :813-822
[6]   Catheter ablation of ventricular tachycardia in patients with coronary heart disease - Part I: Mapping [J].
Delacretaz, E ;
Stevenson, WG .
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 2001, 24 (08) :1261-1277
[7]   Identification of distinct electrocardiographic patterns from the basal left ventricle: Distinguishing medial and lateral sites of origin in patients with idiopathic ventricular tachycardia [J].
Dixit, S ;
Gerstenfeld, EP ;
Lin, D ;
Callans, DJ ;
Hsia, HH ;
Nayak, HM ;
Zado, E ;
Marchlinski, FE .
HEART RHYTHM, 2005, 2 (05) :485-491
[8]   LOCALIZED REENTRY - MECHANISM OF INDUCED SUSTAINED VENTRICULAR-TACHYCARDIA IN CANINE MODEL OF RECENT MYOCARDIAL-INFARCTION [J].
GARAN, H ;
RUSKIN, JN .
JOURNAL OF CLINICAL INVESTIGATION, 1984, 74 (02) :377-392
[9]  
Grimm W., 2001, CARD ELECTROPHYSIOL, V5, P328
[10]   Right and left ventricular outflow tract tachycardias: Evidence for a common electrophysiologic mechanism [J].
Iwai, Sei ;
Cantillon, Daniel J. ;
Kim, Robert J. ;
Markowitz, Steven M. ;
Mittal, Suneet ;
Stein, Kenneth M. ;
Shah, Bindi K. ;
Yarlagadda, Ravi K. ;
Cheung, Jim W. ;
Tan, Vivian R. ;
Lerman, Bruce B. .
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, 2006, 17 (10) :1052-1058