Monitoring the Coating Thickness of Pharmaceutical Tablets with MaxGWMA Control Chart

被引:2
作者
Thanh-Lam Nguyen [1 ]
Shu, Ming-Hung [2 ]
Hsu, Bi-Min [3 ]
机构
[1] Natl Kaohsiung Univ Appl Sci, Grad Inst Mech & Precis Engn, Kaohsiung 80778, Taiwan
[2] Natl Kaohsiung Univ Appl Sci, Dept Ind Engn & Management, Kaohsiung 80778, Taiwan
[3] Cheng Shiu Univ, Dept Ind Engn & Management, Kaohsiung 83347, Taiwan
来源
ADVANCED MATERIALS DESIGN AND MECHANICS II | 2013年 / 372卷
关键词
MaxGWMA; Control chart; Coating thickness; Pharmaceutical coating; VARIABILITY;
D O I
10.4028/www.scientific.net/AMM.372.325
中图分类号
TU [建筑科学];
学科分类号
0813 ;
摘要
So as to monitor and detect small shifts in the mean and variability of a manufacturing process, exponentially weighted moving average (EWMA) control charts are widely employed. Some of its extensions have been proposed to improve its performance. Among them, the Maximum generally weighted moving average (MaxGWMA) control chart is found as the superior. In the industry of coating pharmaceutical tablets, controlling the thickness of the coating layer containing active pharmaceutical ingredients is of great importance and in order to keep track on the coating quality, various methods using modern technologies have been proposed. However, decision support systems on the status of the coating process are not fully developed. Hence, in this study, MaxGWMA control chart was proposed to monitor the coating thickness of the tablets so that any small shift in the coating process can be quickly detected and further corrective actions can be implemented to make the process in control.
引用
收藏
页码:325 / +
页数:3
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