Aspergillus alabamensis, a New Clinically Relevant Species in the Section Terrei

被引:57
作者
Balajee, S. Arunmozhi [1 ]
Baddley, John W. [2 ,3 ]
Peterson, Stephen W. [4 ]
Nickle, David [5 ]
Varga, Janos [6 ,7 ]
Boey, Angeline [1 ]
Lass-Floerl, Cornelia [8 ]
Frisvad, Jens C. [9 ]
Samson, Robert A. [6 ]
机构
[1] Ctr Dis Control & Prevent, Mycot Dis Branch, Atlanta, GA 30333 USA
[2] Univ Alabama, Div Infect Dis, Birmingham, W Midlands, England
[3] Birmingham Vet Affairs Med Ctr, Birmingham, AL USA
[4] USDA, Natl Ctr Agr Utilizat Res, Peoria, IL USA
[5] Univ Washington, Dept Microbiol, Seattle, WA 98195 USA
[6] CBS Fungal Biodivers Ctr, Utrecht, Netherlands
[7] Univ Szeged, Dept Microbiol, Fac Sci & Informat, Szeged, Hungary
[8] Med Univ Innsbruck, Dept Hyg Microbiol & Social Med, Innsbruck, Austria
[9] Tech Univ Denmark, Ctr Microbial Biotechnol, Biocentrum DTU, DK-2800 Lyngby, Denmark
关键词
PULMONARY ASPERGILLOSIS; POLYPHASIC TAXONOMY; FUMIGATUS; NEOSARTORYA; EPIDEMIOLOGY; INFECTIONS; EXPERIENCE;
D O I
10.1128/EC.00272-08
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Phylogenetic analyses of sequences generated from portions of three genes coding for the proteins enolase (enoA), beta-tubulin (benA), and calmodulin (calM) of a large number of isolates within the section Terrei, genus Aspergillus, revealed the presence of a new cryptic species within this section, Aspergillus alabamensis. Most members of this new cryptic species were recovered as colonizing isolates from immunocompetent patient populations, had decreased in vitro susceptibilities to the antifungal drug amphotericin B, and were morphologically similar to but genetically distinct from Aspergillus terreus isolates.
引用
收藏
页码:713 / 722
页数:10
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