Neuromodulation for Eating Disorders: Obesity and Anorexia

被引:6
作者
Gorgulho, Alessandra A. [1 ,2 ,3 ]
Pereira, Julio L. B. [1 ,2 ]
Krahl, Scott [1 ,4 ]
Lemaire, Jean-Jacques [5 ,6 ]
De Salles, Antonio [1 ,2 ,3 ]
机构
[1] Univ Calif Los Angeles, David Geffen Sch Med, Dept Neurosurg, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, David Geffen Sch Med, Dept Radiat Oncol, Los Angeles, CA 90095 USA
[3] Hosp Coracao, HCor Neurosci, BR-05005000 Paraiso, Sao Paulo, Brazil
[4] VA Great Los Angeles Healthcare Hosp, Los Angeles, CA USA
[5] Univ Hosp, Neurosurg Serv, Clermont Ferrand, France
[6] Auvergne Univ, EA Image Guided Clin Neurosci & Connecto 7292, Clermont Ferrand, France
关键词
Eating disorders; Neuromodulation; Deep brain stimulation; Hypothalamus; DEEP BRAIN-STIMULATION; FOOD-INTAKE; VENTROMEDIAL HYPOTHALAMUS; ELECTRICAL-STIMULATION; BODY-WEIGHT; LATERAL HYPOTHALAMUS; CHILDHOOD OVERWEIGHT; BARIATRIC SURGERY; NERVOSA; LEPTIN;
D O I
10.1016/j.nec.2013.08.005
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Extremes of eating disorders (ED) have become prevalent in both developed and developing countries. Available therapies, though largely effective, fail in a substantial number of patients and carry considerable side effects. Morbid obesity and anorexia nervosa (AN) represent important causes of morbidity and mortality among young adults. Morbid obesity affects disproportionate numbers of children. AN is also important for its high mortality in young adults. The challenges of effectively treating AN are well recognized. In this article, important aspects of ED are reviewed in detail and novel approaches to the treatment of ED are proposed.
引用
收藏
页码:147 / +
页数:12
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