A Simple Route to Prepare Monodisperse Au NP-Decorated, Dye-doped, Superparamagnetic Nanocomposites for Optical, MR, and CT Trimodal Imaging

被引:44
作者
Dong, Wenjie [1 ]
Li, Yongsheng [1 ]
Niu, Dechao [1 ]
Ma, Zhi [3 ]
Liu, Xiaohang [4 ]
Gu, Jinlou [1 ]
Zhao, Wenru [1 ]
Zheng, Yuanyi [2 ]
Shi, Jianlin [1 ,5 ]
机构
[1] E China Univ Sci & Technol, Sch Mat Sci & Engn, Minist Educ, Lab Low Dimens Mat Chem,Key Lab Ultrafine Mat, Shanghai 200237, Peoples R China
[2] Chongqing Med Univ Chongqing, Affiliated Hosp 2, Chongqing 400010, Peoples R China
[3] Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China
[4] Fudan Univ, Shanghai Canc Ctr, Dept Radiol, Shanghai 200032, Peoples R China
[5] Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China
基金
中国国家自然科学基金;
关键词
gold nanoparticles; superparamagnetics; computed tomography; magnetic resonance imaging; nanocomposites; GOLD NANOPARTICLES; PHOTOTHERMAL THERAPY; FACILE SYNTHESIS; CANCER-TREATMENT; DRUG-DELIVERY; FABRICATION; NANOPROBES; PLATFORM; UNIFORM; DESIGN;
D O I
10.1002/smll.201202649
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Monodisperse and uniform AuNP-decorated, dye-doped, superparamagnetic nanocomposites (Fe3O4@dye-hybrid@Au) are fabricated by using a simple method in which the Au NP formation and their attachment onto the core surface via S-Au covalent bonds proceeds almost simultaneously in a one-pot synthesis. The as-synthesized nanocomposites can simultaneously enhance the contrast effects for MR, CT, and cellular-sensitive optical imaging. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:2500 / 2508
页数:9
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