L-asparaginase-induced reversible posterior leukoencephalopathy syndrome in a child with acute lymphoblastic leukemia

被引：26
作者：
Rathi, B
Azad, RK
Vasudha, N
Hissaria, P
Sawlani, V
Gupta, RK
机构：
[1] Sanjay Gandhi Postgrad Inst Med Sci, Dept Radiol, Lucknow 226014, Uttar Pradesh, India
[2] Sanjay Gandhi Postgrad Inst Med Sci, Dept Immunol, Lucknow 226014, Uttar Pradesh, India
来源：
PEDIATRIC NEUROSURGERY | 2002年 / 37卷 / 04期
关键词：
L-asparaginase; acute lymphoblastic leukemia; reversible posterior leukoencephalopathy; MRI;
D O I：
10.1159/000065395
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Reversible posterior leukoencephalopathy syndrome (RPLS) is being increasingly described with various etiologies even in the absence of hypertension. We present an 11-year-old patient with acute lymphoblastic leukemia who presented with seizures while on treatment with L-asparaginase. MRI showed bilaterally symmetrical nonenhancing occipital lesions characteristic of RPLS. L-Asparaginase-induced RPLS is a rare cause of neurological symptoms in patients on induction chemotherapy Copyright (C) 2002 S. Karger AG, Basel.
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收藏
页码：203 / 205
页数：3
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