Reliability, validity, and responsiveness of the short form 36 (SF-36) health survey questioinnaire in patients with Graves' disease

被引:0
|
作者
Yu, Jing [1 ,2 ]
Tang, Yi-Yuan [1 ,3 ]
机构
[1] Dalian Med Univ, Inst Neuroinformat, Dalian 116027, Peoples R China
[2] Dalian Med Univ, Affiliated Hosp 2, Dept Nucl Med, Dalian 116027, Peoples R China
[3] Texas Tech Univ, Dept Psychol, Lubbock, TX 79409 USA
关键词
Graves' disease; reliability; responsiveness; SF-36; validity; QUALITY-OF-LIFE; RHEUMATOID-ARTHRITIS; SURVEY QUESTIONNAIRE; WHITEHALL II; FOLLOW-UP; HYPERTHYROIDISM; DISORDERS; ANXIETY; VALIDATION; DEPRESSION;
D O I
10.5372/1905-7415.0703.191
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Background: The SF-36 as a generic instrument has been used widely to evaluate health-related quality of life in both healthy subjects and groups of patients. However, no data can be found on its performance in patients with Graves' disease. Hence, this study aimed to assess the reliability, validity, and responsiveness of the SF-36 in a Chinese population of patients with Graves' disease. Methods: A total of 325 patients with Graves' disease completed interviews that included the SF-36. Internal consistency was measured by Cronbach's alpha and item-scale correlations. The validity of the SF-36 was studied by means of factor analysis and the association of this scale with sociodemographic and clinical variables. A standardized response mean was used to assess the responsiveness of the SF-36 to change. Results: Cronbach's a coefficients surpassed the 0.70 criteria for seven subscales and 0.63 for the SF subscale indicating good internal consistency. The correlation coefficients between items and the remainder of the same subscale ranged from 0.51 to 0.96, which were all higher than with other subscales. A principal components factor analysis with varimax rotation identified eight factors. Hamilton Anxiety Rating Scale (HARS) scores correlated negatively to scores at the physical functioning, general health, social functioning, vitality, and role limitations due to emotional problems SF-36 subscales, while HARS scores correlated negatively only to scores on the mental health SF-36 subscale. No correlations were found between SF-36 scores and the levels of thyroid hormones. Responsiveness to improvements in health status was acceptable overall (standardized response means 0.33-0.88). Conclusion: The Chinese (mainland) version of the SF-36 is a suitable instrument that can be used in patients with Graves' disease.
引用
收藏
页码:391 / 397
页数:7
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