Metabolic Imaging in Parkinson Disease

被引：72

作者：

Meles, Sanne K. ^{[1
]}

Teune, Laura K. ^{[1
]}

de Jong, Bauke M. ^{[1
]}

Dierckx, Rudi A. ^{[2
,3
]}

Leenders, Klaus L. ^{[1
]}

机构：

[1] Univ Groningen, Univ Med Ctr Groningen, Dept Neurol, Groningen, Netherlands

[2] Univ Groningen, Univ Med Ctr Groningen, Dept Nucl Med & Mol Imaging, Groningen, Netherlands

[3] Univ Ghent, Univ Hosp Gent, Dept Nucl Med, Ghent, Belgium

来源：

JOURNAL OF NUCLEAR MEDICINE | 2017年 / 58卷 / 01期

关键词：

Parkinson's disease; FDG-PET; metabolism; imaging; networks; MILD COGNITIVE IMPAIRMENT; SLEEP BEHAVIOR DISORDER; DRUG-NAIVE PATIENTS; NETWORK ACTIVITY; BRAIN NETWORKS; LEWY BODIES; CEREBRAL HYPOMETABOLISM; DIFFERENTIAL-DIAGNOSIS; DEMENTIA; PET;

D O I：

10.2967/jnumed.116.183152

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

This review focuses on recent human 18F-FDG PET studies in Parkinson disease. First, an overview is given of the current analytic approaches to metabolic brain imaging data. Next, we discuss how 18F-FDG PET studies have advanced understanding of the relation between distinct brain regions and associated symptoms in Parkinson disease, including cognitive decline. In addition, the value of 18F-FDG PET studies in differential diagnosis, identifying prodromal patients, and the evaluation of treatment effects are reviewed. Finally, anticipated developments in the field are addressed.

引用

页码：23 / 28

页数：6

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