Metabolic Imaging in Parkinson Disease

被引：72

作者：

Meles, Sanne K. ^{[1
]}

Teune, Laura K. ^{[1
]}

de Jong, Bauke M. ^{[1
]}

Dierckx, Rudi A. ^{[2
,3
]}

Leenders, Klaus L. ^{[1
]}

机构：

[1] Univ Groningen, Univ Med Ctr Groningen, Dept Neurol, Groningen, Netherlands

[2] Univ Groningen, Univ Med Ctr Groningen, Dept Nucl Med & Mol Imaging, Groningen, Netherlands

[3] Univ Ghent, Univ Hosp Gent, Dept Nucl Med, Ghent, Belgium

来源：

JOURNAL OF NUCLEAR MEDICINE | 2017年 / 58卷 / 01期

关键词：

Parkinson's disease; FDG-PET; metabolism; imaging; networks; MILD COGNITIVE IMPAIRMENT; SLEEP BEHAVIOR DISORDER; DRUG-NAIVE PATIENTS; NETWORK ACTIVITY; BRAIN NETWORKS; LEWY BODIES; CEREBRAL HYPOMETABOLISM; DIFFERENTIAL-DIAGNOSIS; DEMENTIA; PET;

D O I：

10.2967/jnumed.116.183152

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

This review focuses on recent human 18F-FDG PET studies in Parkinson disease. First, an overview is given of the current analytic approaches to metabolic brain imaging data. Next, we discuss how 18F-FDG PET studies have advanced understanding of the relation between distinct brain regions and associated symptoms in Parkinson disease, including cognitive decline. In addition, the value of 18F-FDG PET studies in differential diagnosis, identifying prodromal patients, and the evaluation of treatment effects are reviewed. Finally, anticipated developments in the field are addressed.

引用

页码：23 / 28

页数：6

共 47 条

[1] Low clinical diagnostic accuracy of early vs advanced Parkinson disease Clinicopathologic study [J].

Adler, Charles H. ;

Beach, Thomas G. ;

Hentz, Joseph G. ;

Shill, Holly A. ;

Caviness, John N. ;

Driver-Dunckley, Erika ;

Sabbagh, Marwan N. ;

Sue, Lucia I. ;

Jacobson, Sandra A. ;

Belden, Christine M. ;

Dugger, Brittany N. .

NEUROLOGY, 2014, 83 (05) :406-412

[2] The conception of FDG-PET imaging [J].

Alavi, A ;

Reivich, M .

SEMINARS IN NUCLEAR MEDICINE, 2002, 32 (01) :2-5

[3]

[Anonymous], SLEEP MED REV

[4] Functional neuroimaging and clinical features of drug naive patients with de novo Parkinson's disease and probable RBD [J].

Arnaldi, Dario ;

Morbelli, Silvia ;

Brugnolo, Andrea ;

Girtler, Nicola ;

Picco, Agnese ;

Ferrara, Michela ;

Accardo, Jennifer ;

Buschiazzo, Ambra ;

de Carli, Fabrizio ;

Pagani, Marco ;

Nobili, Flavio .

PARKINSONISM & RELATED DISORDERS, 2016, 29 :47-53

[5] MDS research criteria for prodromal Parkinson's disease [J].

Berg, Daniela ;

Postuma, Ronald B. ;

Adler, Charles H. ;

Bloem, Bastiaan R. ;

Chan, Piu ;

Dubois, Bruno ;

Gasser, Thomas ;

Goetz, Christopher G. ;

Halliday, Glenda ;

Joseph, Lawrence ;

Lang, Anthony E. ;

Liepelt-Scarfone, Inga ;

Litvan, Irene ;

Marek, Kenneth ;

Obeso, Jose ;

Oertel, Wolfgang ;

Olanow, C. Warren ;

Poewe, Werner ;

Stern, Matthew ;

Deuschl, Guenther .

MOVEMENT DISORDERS, 2015, 30 (12) :1600-1609

[6] Cerebral Glucose Metabolic Features of Parkinson Disease and Incident Dementia: Longitudinal Study [J].

Bohnen, Nicolaas I. ;

Koeppe, Robert A. ;

Minoshima, Satoshi ;

Giordani, Bruno ;

Albin, Roger L. ;

Frey, Kirk A. ;

Kuhl, David E. .

JOURNAL OF NUCLEAR MEDICINE, 2011, 52 (06) :848-855

[7] THE METABOLIC TOPOGRAPHY OF PARKINSONISM [J].

EIDELBERG, D ;

MOELLER, JR ;

DHAWAN, V ;

SPETSIERIS, P ;

TAKIKAWA, S ;

ISHIKAWA, T ;

CHALY, T ;

ROBESON, T ;

MARGOULEFF, D ;

PRZEDBORSKI, S ;

FAHN, S .

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1994, 14 (05) :783-801

[8] A follow up study of non-demented patients with primary visual cortical hypometabolism: Prodromal dementia with Lewy bodies [J].

Fujishiro, Hiroshige ;

Iseki, Eizo ;

Kasanuki, Koji ;

Chiba, Yuhei ;

Ota, Kazumi ;

Murayama, Norio ;

Sato, Kiyoshi .

JOURNAL OF THE NEUROLOGICAL SCIENCES, 2013, 334 (1-2) :48-54

[9] Posterior parietooccipital hypometabolism may differentiate mild cognitive impairment from dementia in Parkinson's disease [J].

Garcia-Garcia, David ;

Clavero, Pedro ;

Gasca Salas, Carmen ;

Lamet, Isabel ;

Arbizu, Javier ;

Gonzalez-Redondo, Rafael ;

Obeso, Jose A. ;

Rodriguez-Oroz, Maria C. .

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2012, 39 (11) :1767-1777

[10] Significance of visual hallucinations and cerebral hypometabolism in the risk of dementia in Parkinson's disease patients with mild cognitive impairment [J].

Gasca-Salas, Carmen ;

Clavero, Pedro ;

Garcia-Garcia, David ;

Obeso, Jose A. ;

Rodriguez-Oroz, Maria C. .

HUMAN BRAIN MAPPING, 2016, 37 (03) :968-977

← 1 2 3 4 5 →